The microbial pan-genome

TL;DR: This study detects sequence randomness based on a collection of eight statistical random tests and investigates the randomness variation of coding sequences with an application to Escherichia coli, showing that core/essential genes are more random than specific/non-essential genes and indicating that sequence randomity indeed increases over time.

TL;DR: Research into the pathogenesis of the infections it causes are case studies in understanding the molecular basis of the variation in gene expression and gene sequences that are critical to its commensal and virulence behaviour and for the strategies that can be pursued to prevent H. influenzae diseases through vaccines.

TL;DR: The Gram-negative bacterium Aeromonas salmonicida is of veterinary importance as many taxa belonging to the different subspecies are known to infect fish, thus causing important livestock losses worldwide, and with the advances in sequencing technologies, some studies found differences in the mobilome between European and Canadian strains.

TL;DR: This analysis has identified genetic features encoding putative factors controlling host-specificity in S. Pullorum and identified core-genome differences between these two serovars, which can be applied to other bacteria to uncover the genome difference between clades.

TL;DR: Over 1.2 million previously unknown genes represented in these samples, including more than 782 new rhodopsin-like photoreceptors are identified, suggesting substantial oceanic microbial diversity.

TL;DR: The genomic sequence of six strains representing the five major disease-causing serotypes of Streptococcus agalactiae, the main cause of neonatal infection in humans, was generated and Mathematical extrapolation of the data suggests that the gene reservoir available for inclusion in the S. agalactic pan-genome is vast and that unique genes will continue to be identified even after sequencing hundreds of genomes.

TL;DR: Mobile elements within genomes have driven genome evolution in diverse ways and are becoming useful tools for learning more about genome evolution and gene function.

TL;DR: The current review presents the available genomics and biological data on prophages from bacterial pathogens in an evolutionary framework to demonstrate that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving.