Open AccessJournal Article
[The initial prodrome in schizophrenia--core dimensions of experience and behavior].
Paul Møller,Ragnhild Husby +1 more
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TL;DR: This work explores prodromal phenomena and identifies potential core dimensions in 19 first-episode DSM-IV schizophrenia patients and describes experiences and behaviour that appear to be essential components of initial prodromes.
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Abstract: BACKGROUND In order to identify and possibly prevent psychosis at prodromal stages, it is important to learn how patients and families perceive initial prodromes, particularly the prodromal subjective experiences. MATERIALS AND METHODS We explore prodromal phenomena and identify potential core dimensions in 19 first-episode DSM-IV schizophrenia patients and describe experiences and behaviour that appear to be essential components of initial prodromes. RESULTS AND INTERPRETATION The subjects reported serious difficulties interpreting and talking about prodromal experiences at the time when they occurred; this caused delayed identification, the reasons for which we report. Out of eight groups of prodromal experiences we highlight two as tentative core dimensions: [disturbance of perception of self] and [extreme preoccupation by and withdrawal to overvalued ideas]. Four potential dimensions of prodromal behaviour are also identified: (1) leaving school, university or job, or major school truancy, (2) marked and lasting observable shift of interests, (3) marked and lasting social passivity, withdrawal, or isolation, and (4) marked and lasting change in global appearance or behaviour.
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Aripiprazole Long-Acting Injection During First Episode Schizophrenia-An Exploratory Analysis.
Gloria Giordano,Lorenzo Tomassini,Ilaria Cuomo,Emanuela Amici,Filippo Perrini,Gemma Callovini,Alfonso Carannante,Georgios D. Kotzalidis,Sergio De Filippis +8 more
TL;DR: The results support that AOM may improve psychotic symptoms, quality of life, QoL and social functioning in young FEP patients and further studies should compare AOM to its oral formulation in the treatment of young patients with schizophrenia at the outset of their illness.