The importance of cognitive ageing for understanding dementia
TL;DR: It is argued here for the importance of understanding the cognitive ageing process, seen as the decline in various cognitive functions from adulthood to old age, to delay and reduce the population burden of dementia.
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Abstract: A third of those over 80 years of age are likely to have dementia, the lack of a cure requires efforts directed at prevention and delaying the age of onset. We argue here for the importance of understanding the cognitive ageing process, seen as the decline in various cognitive functions from adulthood to old age. The impact of age on cognitive function is heterogeneous and the identification of risk factors associated with adverse cognitive ageing profiles would allow well-targeted interventions, behavioural or pharmacological, to delay and reduce the population burden of dementia. A shift away from binary outcomes such as dementia assessed at one point in time in elderly populations to research on cognitive ageing using repeated measures of cognitive function and starting earlier in the life course would allow the sources of variability in ageing to be better understood.
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Citations
Cross-Sectional and Longitudinal Associations of Different Sedentary Behaviors with Cognitive Performance in Older Adults
Emmanuelle Kesse-Guyot,Hélène Charreire,Hélène Charreire,Valentina A. Andreeva,Mathilde Touvier,Serge Hercberg,Pilar Galan,Jean-Michel Oppert,Jean-Michel Oppert +8 more
TL;DR: In contrast to TV viewing, regular computer use may help maintain cognitive function during the aging process, and specific sedentary behaviors are differentially associated with cognitive performance.
Mediterranean diet and cognitive function: a French study
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TL;DR: This study did not find support for a beneficial effect of MedDiet adherence on cognitive function, irrespective of educational level, which is the strongest indicator of cognitive reserve.
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Association of Coronary Artery Bypass Grafting vs Percutaneous Coronary Intervention With Memory Decline in Older Adults Undergoing Coronary Revascularization.
Elizabeth L. Whitlock,L. Grisell Diaz-Ramirez,Alexander K. Smith,Alexander K. Smith,W. John Boscardin,Kenneth E. Covinsky,Michael S. Avidan,M. Maria Glymour +7 more
TL;DR: In this article, the authors compare the change in the rate of memory decline after coronary artery bypass grafting (CABG) vs. percutaneous coronary intervention (PCI) compared with a nonsurgical method of coronary revascularization (percutaneous artery intervention [PCI]).
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Brain lesions, hypertension and cognitive ageing in the 1921 and 1936 Aberdeen birth cohorts
Alison D. Murray,Roger T. Staff,Christopher J. McNeil,Sima Salarirad,John M. Starr,Ian J. Deary,Lawrence J. Whalley +6 more
TL;DR: The objectives of this study are to model the relative effects of positive (childhood intelligence) and negative (magnetic resonance imaging (MRI)-derived white matter hyperintensities (WMH) predictors of late-life intelligence in two well-characterised normal cohorts aged 68 and 78 and to measure the influence of hypertension on WMH and lifelong cognitive change.
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