Journal Article10.1007/S003840000270
The gastrorectal reflex in women with obstructed defecation.
M.J. Gosselink,W. R. Schouten +1 more
10
TL;DR: Patients with obstructed defecation in whom colonic transit time is normal have an intact gastrorectal reflex according to the tonic response of the rectum to an evoked urge to defecate and rectal sensory perception is significantly impaired both in patients with a normal and in those with a prolonged transit time.
read more
Abstract: This study evaluated the tonic response of the rectum to a meal in women with obstructed defecation. Fifteen control subjects and 60 women with obstructed defecation were studied. Total colonic transit time was normal in 30 patients (group I) and prolonged in the other 30 (group II). After over-night fasting an "infinitely compliant" polyethylene bag was inserted into the rectum. Rectal tone was assessed by measuring variations in bag volume with a computerized electromechanical air injection system. After an adaptation period of 30 min all subjects consumed a 450-kcal liquid meal. Postprandial recordings were continued for 3 h. In a second recording session we investigated the tonic response of the rectum to an evoked urge to defecate. In a third session rectal sensory perception was assessed. Following the meal all controls showed an increase in rectal tone (mean 74.8±17%). Patients in whom colonic transit time was normal showed a similar tonic response. In group II the increase in rectal tone was significantly lower (mean 27.8±10%; P<0.001). Three patients of this group showed no response to a meal at all. All controls showed an increase in rectal tone during an evoked urge to defecate (mean 39.2±9%). In both groups this tonic response was absent or significantly blunted (mean 15.3±6% and 16.4±5%, respectively; P<0.001). In both groups rectal sensory perception was significantly impaired. In conclusion, patients with obstructed defecation in whom colonic transit time is normal have an intact gastrorectal reflex. The increase in rectal tone after a meal is absent or blunted in patients with obstructed defecation in whom transit time is prolonged. The tonic response of the rectum to an evoked urge to defecate as well as rectal sensory perception are significantly impaired both in patients with a normal and in those with a prolonged transit time.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Pathophysiology of constipation in the older adult
TL;DR: Findings from a limited number of clinical studies that utilized objective measures do not support that self-reported constipation increases with age, and changes in GI function associated with aging appear to be relatively subtle based on a limited amount of conflicting data.
110
Pathophysiology of evacuation disorders.
TL;DR: Despite the need for more research, significant advances have been made and current assessments can direct therapy.
53
Home Transcutaneous Electrical Stimulation Therapy to Treat Children With Anorectal Retention: A Pilot Study
Yee Ian Yik,Lefteris Stathopoulos,Lefteris Stathopoulos,John M. Hutson,John M. Hutson,Bridget R. Southwell,Bridget R. Southwell +6 more
TL;DR: A pilot study was performed to test if TES can improve symptoms (defecation and soiling) in children with chronic constipation without STC and transit delay in the anorectum.
19
Biofeedback in faecal incontinence
TL;DR: Electrical stimulation of the anal sphincter is only shown to be effective in one controlled study in which it was combined with biofeedback training, and only four studies provide evidence-based medical criteria.
7
•Dissertation
An assessment of investigations for evacuatory dysfunction
Somnath Palit
- 07 Jan 2016
TL;DR: Prospective comparison of balloon expulsion, anorectal manometry and evacuation proctography for the diagnosis of rectal evacuatory disorder and assessment of Asymptomatic Volunteers using a New High Resolution Manometric Recording System.
4
References
Severe Idiopathic Constipation Is Associated With a Distinctive Abnormality of the Colonic Myenteric Plexus
Shoba Krishnamurthy,Shoba Krishnamurthy,Michael D. Schuffler,Michael D. Schuffler,Charles A. Rohrmann,Charles A. Rohrmann,Charles E. Pope,Charles E. Pope +7 more
TL;DR: Severe idiopathic constipation is associated with a pathologically identifiable abnormality of the myenteric plexus, which appears different from anything previously described in intestinal pseudoobstruction.
277
Colonic mass movements in idiopathic chronic constipation.
TL;DR: The data suggest that one pathophysiological mechanism of constipation may be decreased propulsive activity, and a circadian pattern, with a significant difference between day and night distribution, was documented in both groups.
247
Manometric investigation of high-amplitude propagated contractile activity of the human colon
Gabrio Bassotti,M. Gaburri +1 more
TL;DR: In this paper, the authors investigated colonic peristalsis (highamplitude propagated contractions; HAPCs) in 20 healthy volunteers by means of a colonoscopically positioned manometric probe and low compliance infusion system.
229
Variation of muscle tone in the human colon.
TL;DR: The barostat revealed a motor phenomenon not readily apparent by conventional manometry, which has the potential to explore another possibly important aspect of colonic function in humans.
136
Differences in colonic tone and phasic response to a meal in the transverse and sigmoid human colon.
TL;DR: There are quantitatively different but qualitatively similar phasic and tonic responses to the meal in the two colonic regions, and differences in the viscoelastic and luminal dimensions may partly account for these differences in Tonic responses.
122