Journal Article10.1016/J.CLINPH.2011.04.027
The cerebellum in dystonia - help or hindrance?
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TL;DR: It is proposed that abnormal, likely compensatory activity of the cerebellum is an important factor within pathophysiological models of dystonia.
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About: This article is published in Clinical Neurophysiology. The article was published on 01 Jan 2012. The article focuses on the topics: Focal dystonia & Dystonia.
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Citations
Cerebellar networks with the cerebral cortex and basal ganglia
TL;DR: These findings elucidate the neuroanatomical substrate for cerebellar involvement in non-motor functions mediated by the prefrontal and posterior parietal cortex, as well as in processes traditionally associated with the basal ganglia.
726
Dystonia as a Network Disorder: What is the Role of the Cerebellum?
TL;DR: The dystonias are a group of disorders defined by sustained or intermittent muscle contractions that result in involuntary posturing or repetitive movements as discussed by the authors, and they have been attributed to dysfunction of the basal ganglia, particularly the cerebellum.
250
The Focal Dystonias: Current Views and Challenges for Future Research
Hyder A. Jinnah,Alfredo Berardelli,Cynthia L. Comella,Giovanni Defazio,Mahlon R. DeLong,Stewart A. Factor,Wendy R. Galpern,Mark Hallett,Christy L. Ludlow,Joel S. Perlmutter,Ami Rosen +10 more
TL;DR: A brief review of the clinical manifestations of the adult‐onset focal dystonias is provided, focusing attention on less well understood clinical manifestations that need further study.
Current Opinions and Areas of Consensus on the Role of the Cerebellum in Dystonia
Vikram G. Shakkottai,Amit Batla,Kailash P. Bhatia,William T. Dauer,Christian Dresel,Martin Niethammer,David Eidelberg,Robert S. Raike,Yoland Smith,Hyder A. Jinnah,Ellen J. Hess,Sabine Meunier,Mark Hallett,Rachel Fremont,Kamran Khodakhah,Mark S. LeDoux,Traian Popa,Cecile Gallea,Stéphane Lehéricy,Andreea C. Bostan,Peter L. Strick +20 more
TL;DR: Overall points of consensus include: neuronal dysfunction originating in the cerebellum can drive dystonic movements in rodent model systems and data about brain structure, cerebellar metabolism, and noninvasive Cerebellar stimulation that support (or not) a role for the cereBellum in human dystonia.
Cerebellar modulation of human associative plasticity
Masashi Hamada,Gionata Strigaro,N. Murase,Anna Sadnicka,Joseph M. Galea,Mark J. Edwards,John C. Rothwell +6 more
TL;DR: It is shown that modulation of cerebellar activity using transcranial direct current stimulation can abolish associative plasticity in the motor cortex, but only for sensory/motor stimuli paired at 25 ms, not at 21.5 ms.
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References
Parallel Organization of Functionally Segregated Circuits Linking Basal Ganglia and Cortex
TL;DR: The basal ganglia serve primarily to integrate diverse inputs from the entire cerebral cortex and to "funnel" these influences, via the ventrolateral thalamus, to the motor cortex.
Influence of interhemispheric interactions on motor function in chronic stroke
Nagako Murase,Julie Duque,Julie Duque,Riccardo Mazzocchio,Riccardo Mazzocchio,Leonardo G. Cohen +5 more
TL;DR: An abnormally high interhemispheric inhibitory drive from M1intact hemisphere to M1lesioned hemisphere in the process of generation of a voluntary movement by the paretic hand is document, conceivable that this abnormality could adversely influence motor recovery in some patients with subcortical stroke.
1.4K
Cerebellar Projections to the Prefrontal Cortex of the Primate
TL;DR: The observations indicate that the cerebellum influences several areas of prefrontal cortex via the thalamus, and separate output channels exist in the dentate to influence motor and cognitive operations.
1K
The cerebellum communicates with the basal ganglia.
Eiji Hoshi,Eiji Hoshi,Léon Tremblay,Jean Féger,Peter L Carras,Peter L. Strick,Peter L. Strick +6 more
TL;DR: Using transneuronal transport of rabies virus in macaques, it is found that a disynaptic pathway links an output stage of cerebellar processing, the dentate nucleus, with an input stage of basal gangliaprocessing, the striatum.
832
The basal ganglia communicate with the cerebellum
TL;DR: Results provide the anatomical substrate for substantial two-way communication between the basal ganglia and cerebellum, and suggest that the two subcortical structures may be linked together to form an integrated functional network.
771