The catecholamine hypothesis of depressions: Further arguments

TL;DR: In this article, a series of depression theories, in which neuroplasticity theories are the most recent addition, are investigated, which illustrates how the epistemological and technological aspects of research intertwine in the history of psychiatry in general and the field of depression in particular.

TL;DR: It is concluded that supplement-induced nutritional ketosis leads to metabolic changes and improvements, for example, in mitochondrial function and inflammatory processes, and suggest that development of specific adjunctive ketogenic protocols for psychiatric diseases should be actively pursued.

TL;DR: Rosenblatt et al, 9 in 1959, were among the first to specifically suggest that changes in brain norepinephrine (NEP) may be involved in depression, and hypothesized that the depressive state might be associated with a relative decrease of nore Alpinephrine.

TL;DR: For those who are starting to learn about something new and feel curious about this book, it's easy then to get this book and feel how this book will give you more exciting lessons.

TL;DR: A review of the studies of clinical efficacy of tricyclic compounds in the treatment of depression supports the general view that imipramine and amitriptyline are more effective than placebo as discussed by the authors.

TL;DR: A review of the studies of clinical efficacy of the tricyclic compounds in the treatment of depression supports the general view that imipramine and amitriptyline are more effective than placebo, and that amitripyline may even be a little moreeffective than imipramsine.