The Biology of Hernia Formation
195
TL;DR: Defects in wound healing and extracellular matrix synthesis contribute to the high incidence of incisional hernia formation following laparotomy.
read more
About: This article is published in Surgical Clinics of North America. The article was published on 01 Feb 2008. and is currently open access. The article focuses on the topics: Incisional hernia & Hernia.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Incidence of and risk factors for incisional hernia after abdominal surgery
Keita Itatsu,Yukihiro Yokoyama,Gen Sugawara,H. Kubota,Y. Tojima,Yasuhiro Kurumiya,H. Kono,H. Yamamoto,Masahiko Ando,Masato Nagino +9 more
TL;DR: A small number of studies have estimated the incidence of incisional hernia after abdominal surgery, but these studies are small in comparison with the need to investigate further the cause of hernia.
250
Connective tissue alteration in abdominal wall hernia
TL;DR: The aim of this study was to review the literature on specific collagen alterations in abdominal wall hernia formation to assess the need for further research into these mechanisms.
144
Polyvinylidene fluoride: a suitable mesh material for laparoscopic incisional and parastomal hernia repair! A prospective, observational study with 344 patients.
David H. Berger,M. Bientzle +1 more
TL;DR: The laparoscopic repair of incisional and parastomal hernias with meshes made of PVDF (Dynamesh IPOM®) revealed low recurrence and, overall, low complication rates.
139
•Journal Article
Advances in Suture Material for Obstetric and Gynecologic Surgery
TL;DR: The wound healing process and the biomechanical properties of currently available suture materials are discussed to better understand how to choose suture material in obstetrics and gynecology.
121
Human monocyte activation by biologic and biodegradable meshes in vitro.
Sean B. Orenstein,Yi Qiao,Manjot Kaur,Ulrike Klueh,Ulrike Klueh,Donald L. Kreutzer,Donald L. Kreutzer,Y. W. Novitsky +7 more
TL;DR: It is demonstrated that human macrophages are activated by human dermis-derived biologic and biodegradable meshes in vitro, and a wide range of cytokine and growth factor induction was seen among the different mesh products.
85
References
A Comparison of Suture Repair with Mesh Repair for Incisional Hernia
R W Luijendijk,Wim C. J. Hop,van den Tol Mp,de Lange Dc,Braaksma Mm,Jan N. M. IJzermans,Boelhouwer Ru,de Vries Bc,Salu Mk,Wereldsma Jc,Bruijninckx Cm,J. Jeekel +11 more
TL;DR: Among patients with midline abdominal incisional hernias, mesh repair is superior to suture repair with regard to the recurrence of hernia, regardless of the size of the hernia.
1.9K
Incisional hernia: A 10 year prospective study of incidence and attitudes
Marjorie Mudge,L. E. Hughes +1 more
TL;DR: Recurrence is common after surgical repair but seems to be related to surgical technique, and the possibility of complications occurring from an incisional hernia does not appear to be discussed with patients although obstruction occurred in 14 per cent of patients with troublesome hernia.
1K
Accelerated healing of incisional wounds in rats induced by transforming growth factor-beta.
Thomas A. Mustoe,Glenn F. Pierce,Arlen R. Thomason,Peggy Gramates,Michael B. Sporn,Thomas F. Deuel +5 more
TL;DR: TGF-beta is a potent pharmacologic agent that can accelerate wound healing in rats and is accompanied by an increased influx of mononuclear cells and fibroblasts and by marked increases in collagen deposition at the site of application of TGF- beta.
1K