The ART strategy: sequential assessment of the ART score predicts outcome of patients with hepatocellular carcinoma re-treated with TACE.
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TL;DR: It would have been useful to have seen the individual biochemical constituents of the ChildPugh score and assessed their impact on predicting outcome, and an alternative score for predicting patient outcome after TACE is available.
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About: This article is published in Journal of Hepatology. The article was published on 01 Jul 2014. and is currently open access. The article focuses on the topics: Hepatocellular carcinoma.
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Citations
Hepatocellular carcinoma review: current treatment, and evidence-based medicine.
Ali Raza,Gagan Sood +1 more
TL;DR: An overview of treatment of early and advanced stage HCC based on an extensive review of relevant literature is provided.
467
Transarterial chemoembolization: modalities, indication, and patient selection
TL;DR: New approaches for better patient selection for initial and subsequent TACE treatment schedules will limit the use of TACE to some extent but have the potential to improve outcome for patients at risk for TACE-induced harm.
314
Cancer and liver cirrhosis: implications on prognosis and management
Matthias Pinter,Michael Trauner,Markus Peck-Radosavljevic,Wolfgang Sieghart +3 more
- 01 Mar 2016
TL;DR: This review provides a concise overview about the impact of liver cirrhosis on the management and prognosis of patients with primary liver cancer or non-hepatic malignancies.
261
Treatment of Liver Tumors with Lipiodol TACE: Technical Recommendations from Experts Opinion
Thierry de Baere,Yasuaki Arai,Riccardo Lencioni,Jean Francois H. Geschwind,William S. Rilling,Riad Salem,Osamu Matsui,Michael C. Soulen +7 more
TL;DR: There is no consensus on the standard method of TACE regarding the use of anticancer agents, embolic material, technical details, and the treatment schedule, and a worldwide panel of experts participated in a consensus meeting held on May 10, 2014.
250
The treatment of intermediate stage tumours beyond TACE: From surgery to systemic therapy
Peter R. Galle,Francesco Tovoli,Friedrich Foerster,Marcus A. Wörns,Alessandro Cucchetti,Luigi Bolondi +5 more
TL;DR: This review evaluates the current literature for the treatment strategies for patients with intermediate Barcelona Clinic Liver Cancer (BCLC) B stage HCC and suggests radical approaches such as hepatic resection or even liver transplantation can be considered.
230
References
A simple prognostic scoring system for patients receiving transarterial embolisation for hepatocellular cancer.
L. Kadalayil,R. Benini,L Pallan,James O'Beirne,Laura Marelli,Dominic Yu,Allan Hackshaw,Richard Fox,Philip J. Johnson,A.K. Burroughs,Daniel H. Palmer,Tim Meyer +11 more
TL;DR: The HAP score predicts outcomes in patients with HCC undergoing TACE/TAE and may help guide treatment selection, allow stratification in clinical trials and facilitate meaningful comparisons across reported series.
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The ART-strategy: Sequential assessment of the ART score predicts outcome of patients with hepatocellular carcinoma re-treated with TACE
F. Hucke,Wolfgang Sieghart,Matthias Pinter,Ivo Graziadei,Wolfgang Vogel,Christian Müller,Harald Heinzl,Fredrik Waneck,Michael Trauner,Markus Peck-Radosavljevic +9 more
TL;DR: The sequential assessment of the ART score identifies patients with dismal prognosis prior to each TACE session and remains a valid predictor of OS independent of Child-Pugh score, CRP-levels and tumor characteristics.
112
King's Score: an accurate marker of cirrhosis in chronic hepatitis C
TL;DR: The King's Score is a simple and accurate index for predicting cirrhosis in chronic hepatitis C and confirmed the utility of this index, area under receiver operating characteristic curves 0.94 and 0.89 for Cirrhosis and F3–6, respectively.
Plasma clearance of intravenously injected aspartate aminotransferase isozymes: evidence for preferential uptake by sinusoidal liver cells.
TL;DR: The tissue distribution of the radioactivity following intravenous administration of 125I‐labeled isozymes revealed that the liver is a major organ involved in plasma clearance of these isoz enzymes, supported by the significant retardation in plasma clearing of m‐AAT in hepatectomized as well as CCI4‐intoxicated rats.