Synthesis and characterization of elastic and macroporous chitosan–gelatin cryogels for tissue engineering

TL;DR: Cryogels impregnated with bioluminescent reporter cells provided enhanced survival, higher local retention, and extended engraftment of transplanted cells at the injection site compared with a standard injection technique, and demonstrated long-term release of biomolecules in vivo.

TL;DR: This review covers several important natural proteins and polysaccharides widely used as hydrogels for articular cartilage tissue engineering and the mechanical properties, structures, modification, and structure–performance relationship of theseHydrogels are discussed since the chemical structures and physical properties dictate the in vivo performance and applications of polymer hydrogeled regeneration and repair.

TL;DR: G gelatin–polysaccharide biomaterials benefit from mechanical resilience, high stability, low thermal expansion, improved hydrophilicity, biocompatibility, antimicrobial and anti‐inflammatory properties, and wound healing potential.

TL;DR: This review highlights recent advances in cryogelation techniques and starting materials that can be utilised to synthesise biocompatible and biologically relevant cryogels as well as discussing physicochemical characterisation techniques for these materials.

TL;DR: Research on the tissue engineering of bone and cartilage from the polymeric scaffold point of view is reviews from a biodegradable and bioresorbable perspective.

TL;DR: A tissue engineering approach was developed to produce arbitrary lengths of vascular graft material from smooth muscle and endothelial cells that were derived from a biopsy of vascular tissue, with patency documented up to 24 days by digital angiography.

TL;DR: The ability to manipulate and reconstitute tissue structure and function using chitosan has tremendous clinical implications and is likely to play a key role in cell and gene therapies in coming years.

TL;DR: A tough biodegradable elastomer is designed, synthesized, and characterized from biocompatible monomers that forms a covalently crosslinked, three-dimensional network of random coils with hydroxyl groups attached to its backbone.