Stevioside and rebaudioside A – predominant ent-kaurene diterpene glycosides of therapeutic potential: a review
TL;DR: Gupta et al. as discussed by the authors presented a review of the chemistry of stevioside and rebaudioside A, possible biosynthetic pathways, their metabolism and acceptable daily intake along with a broad spectrum of pharmacological and therapeutic applications.
read more
Abstract: Gupta E., Purwar S., Sundaram S., Tripathi P., Rai G. (2016): Stevioside and rebaudioside A – predominant ent-kaurene diterpene glycosides of therapeutic potential – a review. Czech J. Food Sci., 34: 281–299. Stevia rebaudiana (Bertoni) is a Paraguayan perennial herb of the family Asteraceae. The leaves contain a great amount of secondary metabolites with a wide range of important biological activities commonly known as steviol glycosides which differ in their molecular configuration, power of sweetness and their taste profile. Out of various steviol glycosides, the main compounds of interest are diterpenoid glycosides of ent-kaurene type extracted from the leaves of this plant as non-toxic, thermally stable, low-calorie natural sweeteners stevioside and rebaudioside A. These glycosides are a high-quality sugar substitute or dietary supplement with diverse applications in the medicinal world along with the food and beverage industry. This review article is aimed at the chemistry of stevioside and rebaudioside A, possible biosynthetic pathways, their metabolism and acceptable daily intake along with a broad spectrum of pharmacological and therapeutic applications.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Natural and low-caloric rebaudioside A as a substitute for dietary sugars: A comprehensive review.
Yang Wang,Xiang Luo,Li Chen,Abdullateef Taiye Mustapha,Xiaojie Yu,Cun-Qi Zhou,Clinton E. Okonkwo +6 more
TL;DR: The physicochemical properties, metabolic process, safety, regulatory, health benefits, and biosynthetic pathway of rebaudioside A and summarize the modification methods and state-of-the-art production and purification techniques as mentioned in this paper .
22
An Interdisciplinary Approach Towards Sustainable and Higher Steviol Glycoside Production from In vitro cultures of Stevia rebaudiana.
TL;DR: In this paper , the authors discuss the tissue culture perspectives of S. rebaudiana, primarily focusing on the mineral nutrition, growth regulators and other accessory factors, motioning the optimum growth and development of the plant.
16
Aqueous and alcoholic adducts of steviol and steviol glycosides in food products containing stevia.
TL;DR: The performed experiments prove that water and alkoxy adducts are formed not only during temperature processing of stevioside but also of Stevia and stevia-containing food products.
11
The productivity of Stevia rebaudiana (Bertoni) on dry leaves and steviol glycosides of four varieties grown in six regions of Morocco
TL;DR: In this article, the effects of region and varieties on stevia dry leaf yield, steviol glycoside content, and stevio-glycoside yield under Moroccan conditions were investigated.
10
Therapeutic and Nutraceutical Potential of Bioactive Compounds in Aegle marmelos (L.): An Overview
TL;DR: This review article focuses on exploring novel bioactive compounds of the above plant possessing potential therapeutic and health promoting applications of A. marmelos.
5
References
A revised medium for rapid growth and bio assays with tobacco tissue cultures
Toshio Murashige,Folke Skoog +1 more
TL;DR: In vivo redox biosensing resolves the spatiotemporal dynamics of compartmental responses to local ROS generation and provide a basis for understanding how compartment-specific redox dynamics may operate in retrograde signaling and stress 67 acclimation in plants.
69.6K
The formation and function of plant volatiles: perfumes for pollinator attraction and defense
TL;DR: The rapid progress in elucidating the biosynthetic pathways, enzymes, and genes involved in the formation of plant volatiles allows their physiology and function to be rigorously investigated at the molecular and biochemical levels.
1.2K
Stevia rebaudiana Bertoni, source of a high-potency natural sweetener: A comprehensive review on the biochemical, nutritional and functional aspects
TL;DR: Stevia rebaudiana Bertoni, an ancient perennial shrub of South America, produces diterpene glycosides that are low calorie sweeteners, about 300 times sweeter than saccharose, which are thought to possess antioxidant, antimicrobial and antifungal activity.
662
Stevioside and related compounds: therapeutic benefits beyond sweetness.
TL;DR: This review summarizes the current knowledge of the pharmacological actions, therapeutic applications, pharmacokinetics and safety of stevioside and related compounds and proposes its role as a drug modulator.
467
Shanidar IV, a Neanderthal Flower Burial in Northern Iraq
TL;DR: The discovery of pollen clusters of different kinds of flowers in the grave of one of the Neanderthals, No. IV. at Shanidar cave, Iraq as mentioned in this paper further confirmed the acceptance of the Neanderthals in our line of evolution.
406