1. What are the contributions in "Solid switchable phantom for diffuse optical imaging" ?
The authors propose a simple and reliable solid phantom for mimicking localized absorption changes within a diffusive medium.
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Solid switchable phantom for diffuse optical imaging
Antonio Pifferi,Alessandro Torricelli,Rinaldo Cubeddu,Giovanna Quarto,Rebecca Re,Sanathana Konugolu Venkata Sekar,Lorenzo Spinelli,Andrea Farina,Fabrizio Martelli,Heidrun Wabnitz +9 more
TL;DR: In this paper, a simple and reliable solid phantom for mimicking localized absorption changes within a diffusive medium is proposed, which is based on the equivalence relation stating that any realistic absorption inhomogeneity can be mimicked by a totally absorbing sphere of adequate volume.
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Abstract: We propose a simple and reliable solid phantom for mimicking localized absorption changes within a diffusive medium. The phantom is based on the Equivalence Relation stating that any realistic absorption inhomogeneity can be mimicked by a totally absorbing sphere of adequate volume. Applying this concept, we constructed a solid phantom holding a movable black inclusion to be positioned beneath the source-detector pair (perturbed case) or far from it (unperturbed case). Different absorption perturbations can be mimicked by changing the volume and the position of the black object both in transmittance and reflectance configuration. Time-resolved measurements of transmittance images and a lateral reflectance scan are presented.
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Citations
Tissue phantoms in multicenter clinical trials for diffuse optical technologies - eScholarship
Albert E. Cerussi,Robert V. Warren,Brian Hill,Darren Roblyer,Anais Leproux,Amanda Durkin,Thomas D. O'Sullivan,Sam Keene,Hosain Haghany,Timothy Quang,William M. Mantulin,Bruce J. Tromberg +11 more
- 16 Apr 2012
TL;DR: The development and testing of a series of optically turbid phantoms used in a multi-center American College of Radiology Imaging Network (ACRIN) clinical trial of Diffuse Optical Spectroscopic Imaging (DOSI) are described.
References
Review of tissue simulating phantoms for optical spectroscopy, imaging and dosimetry
TL;DR: This review is an attempt to indicate which sets of phantoms are optimal for specific applications, and provide links to studies that characterize main phantom material properties and recipes.
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Tissue-Like Phantoms for Near-Infrared Fluorescence Imaging System Assessment and the Training of Surgeons
Alec M. De Grand,Stephen Johnson Lomnes,Deborah S. Lee,Matthew Pietrzykowski,Shunsuke Ohnishi,Timothy G. Morgan,Andrew Gogbashian,Rita G. Laurence,John V. Frangioni +8 more
TL;DR: It is demonstrated how calibrated, stable, and inexpensive tissue-like phantoms can be used to calibrate and compare imaging systems, and to train surgeons to operate under NIR fluorescence image guidance.
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Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol
Heidrun Wabnitz,D. R. Taubert,Mikhail Mazurenka,Oliver Steinkellner,Alexander Jelzow,Rainer Macdonald,Daniel Milej,Piotr Sawosz,Michal Kacprzak,Adam Liebert,Robert J. Cooper,Jeremy C. Hebden,Antonio Pifferi,Antonio Pifferi,Andrea Farina,Ilaria Bargigia,Davide Contini,Matteo Caffini,Lucia Zucchelli,Lorenzo Spinelli,Rinaldo Cubeddu,Rinaldo Cubeddu,Alessandro Torricelli +22 more
TL;DR: The "Basic Instrumental Performance" protocol for direct measurement of relevant characteristics is presented and the relevance of the responsivity measure is demonstrated by simulations of diffuse reflectance as a function of source-detector separation and optical properties.
Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol.
Heidrun Wabnitz,Alexander Jelzow,Mikhail Mazurenka,Oliver Steinkellner,Rainer Macdonald,Daniel Milej,Norbert Żołek,Michal Kacprzak,Piotr Sawosz,Roman Maniewski,Adam Liebert,Salavat Magazov,Jeremy C. Hebden,Fabrizio Martelli,Paola Di Ninni,Giovanni Zaccanti,Alessandro Torricelli,Davide Contini,Rebecca Re,Lucia Zucchelli,Lorenzo Spinelli,Rinaldo Cubeddu,Rinaldo Cubeddu,Antonio Pifferi,Antonio Pifferi +24 more
TL;DR: The nEUROPt protocol addresses the characteristic of optical brain imaging to detect, localize, and quantify absorption changes in the brain and could be a useful step toward performance tests for future standards in diffuse optical imaging.
Seven-wavelength time-resolved optical mammography extending beyond 1000 nm for breast collagen quantification
Paola Taroni,Antonio Pifferi,Elena Salvagnini,Lorenzo Spinelli,Alessandro Torricelli,Rinaldo Cubeddu +5 more
TL;DR: The multi-wavelength time-resolved optical mammograph was upgraded to improve its overall performances and extend its spectral coverage up to 1060 nm, with the aim of increasing the measurement sensitivity to the content of collagen in breast tissue.
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