Short-term versus extended anticoagulant treatment for unprovoked venous thromboembolism: A survey on guideline adherence and physicians' considerations
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TL;DR: A wide variety of considerations regarding treatment duration in patients with unprovoked VTE are confirmed, and guidelines' recommendations to prescribe indefinite treatment in absence of contraindications are not always supported by evidence.
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About: This article is published in Thrombosis Research. The article was published on 01 Nov 2019. and is currently open access.
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Citations
Deciding on treatment duration for unprovoked venous thromboembolism: what is important to patients?
Anouk van de Brug,Maria A. de Winter,Marije ten Wolde,Karin A H Kaasjager,Mathilde Nijkeuter +4 more
TL;DR: In this article, patients who felt involved and informed were more satisfied with received care, more aware of risks and benefits of treatment, and more likely to be treatment adherent, while patients were more concerned with risk of recurrent venous thromboembolism rather than risk of bleeding during anticoagulation.
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Treatment Decision-Making of Secondary Prevention After Venous Thromboembolism: Data From the Real-Life START2-POST-VTE Register.
Emilia Antonucci,Ludovica Migliaccio,Maria Abbattista,Antonella Caronna,Sergio De Marchi,Angela Di Giorgio,Rosella Di Giulio,Teresa Lerede,Maria Grazia Garzia,Ida Martinelli,Daniela Mastroiacovo,Marco Marzolo,Elisa Montevecchi,Daniele Pastori,Pasquale Pignatelli,Daniela Poli,Luigi Ria,Angelo Santoliquido,Sophie Testa,Gualtiero Palareti,Start Post Vte Investigators +20 more
TL;DR: Italian doctors stuck to the minimum 3 months AT after VTE, while the secondary or unprovoked nature of the event was not seen as the prevalent factor influencing AT duration which instead was the result of a complex and multifactorial evaluation of each patient.
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How to predict recurrent venous thromboembolism and bleeding? A review of recent advances and their implications.
TL;DR: In this paper , the authors provide a summary of these models and their performance and conclude that these models are rarely used in clinical practice and none of them is incorporated in current guidelines due to insufficient accuracy or insufficient validation.
Long-Term Management of Pulmonary Embolism: A Review of Consequences, Treatment, and Rehabilitation
Anette Arbjerg Højen,Peter Nielsen,Thure Filskov Overvad,Ida Ehlers Albertsen,Frederikus A. Klok,Nanna Rolving,Mette Nørgaard,Anne Gulbech Ording +7 more
TL;DR: Current and emerging evidence on the treatment of specific patient populations, its secondary prevention, long-term complications, and the unmet need for rehabilitation has the potential to change clinical practice for the benefit of the patients.
An international survey of clinicians regarding their management of venous thromboembolism following the initial 3-6 months of anticoagulation
E. Banham-Hall,A. Allison,A. Santarsieri,M. Gohel,Maeve P. Crowley,K. Sheares,K. Sheares,Will Thomas +7 more
TL;DR: There is a lack consensus among clinicians that manage VTE regarding which patients require 3–6 months versus indefinite anticoagulation, and for patients with unprovoked VTE or VTE associated with a major transient risk factor there is treatment consensus.
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References
Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report
Clive Kearon,Elie A. Akl,Elie A. Akl,Joseph Ornelas,Allen J. Blaivas,David Jiménez,Henri Bounameaux,Menno V. Huisman,Christopher S. King,Timothy A. Morris,Namita Sood,Scott M. Stevens,Janine R.E. Vintch,Philip S. Wells,Scott C. Woller,Lisa K. Moores +15 more
TL;DR: Recommendations on 12 topics that were in the 9th edition of these guidelines are updated, and 3 new topics are addressed.
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TL;DR: Guidelines summarize and evaluate all available evidence at the time of the writing process, on a particular issue with the aim of assisting health professionals in selecting the best management strategies for an individual patient, with a given condition, taking into account the impact on outcome.
Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
Clive Kearon,Susan R. Kahn,Giancarlo Agnelli,Samuel Z. Goldhaber,Gary E. Raskob,Anthony J. Comerota +5 more
TL;DR: This chapter about treatment for venous thromboembolic disease is part of the American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition) and indicates that the benefits do or do not outweigh risks, burden, and costs.
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Thrombosis A Major Contributor to Global Disease Burden
Gary E. Raskob,Pantep Angchaisuksiri,Alicia N. Blanco,Harry R. Büller,Alexander Gallus,Beverley J. Hunt,Elaine M. Hylek,Ajay K. Kakkar,Stavros Konstantinides,M. McCumber,Yukio Ozaki,Aaron M. Wendelboe,Jeffrey I. Weitz +12 more
TL;DR: A systematic review of the literature on the global burden of venous thromboembolism (VTE) in low-, middle-, and high-income countries was performed in this article.
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TL;DR: Direct oral anticoagulant treatment are first-line treatment options for venous thromboembolism because they are associated with a lower risk of bleeding than vitamin K antagonists and are easier to use.
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