Serum iron and unsaturated iron-binding capacity in the -thalassaemia trait: their relation to the levels of haemoglobins A, A 2 , and F.

TL;DR: The methods of quantifying Hb F are described together with pitfalls in undertaking these laboratory tests with particular emphasis on automated high‐performance liquid chromatography and capillary electrophoresis.

TL;DR: Close monitoring of the maternal and fetal condition during pregnancy is essential, and various treatments, such as blood transfusion or postpartum prophylaxis for thromboembolism, may be indicated.

TL;DR: Nine patients have been observed with homozygous β thalassaemia in each of whom one parent has a normal level of Hb A2 and these families have been divided into two groups on the basis of clinical, haematological and globin chain synthesis studies.

TL;DR: There is no general agreement about the best therapy of myxoedema coma, but common practice to give thyroxine in doses of 0 05 mg daily by mouth combined with triiodothyronine 20 Fg twice daily by intramuscular injection together with hydrocortisone hemisuccinate 50 mg twice daily.

Abstract: The Amphetamines: Toxicity and Addiction by Oriana Josseau Kalant PhD pp xii+151 48s Toronto: University ofToronto Press 1966 London: Oxford University Press No one will deny that the appearance of this monograph is timely. Reports on drug addiction, more or less sensational, abound not only in the lay press but in the medical journals as well. The term is used loosely, opium, heroin, cannabis, the amphetamines and the hallucinogens all tending to fall into the same heap and, as the London Times pointed out recently in a leading article, 'Drugs, searches, sex and the swinging city have been built into one single hateful promotion'. This work by Dr Kalant gives a welcome return to objectivity. It contributes nothing new but, if not quite exhaustive, gives a masterly and succinct review of the knowledge to date. To the medical man it will afford a convenient and readable form of enlightenment on this very controversial subject. Students, too, will learn from it a great deal which may stand them in good stead, as much personally as it will professionally. But, above all, this should be obligatory reading for all those editors, radio and television producers, correspondents and moral arbiters who are so impatient to express themselves without paying sufficient attention to the facts that are available. As far as the amphetamines are concerned, there can be no excuse now. Dare we ask that Dr Kalant and her sponsors, the Alcoholism and Drug Addiction Research Foundation of Ontario, now proceed to deal similarly with the opiates, with cannabis and with the hallucinogens?

TL;DR: The present study was undertaken in order to obtain information on the frequciicy of carriers of the abnormal trait in Greece and to collect data regarding the haematological and biocheniical abnormalities of such carriers in a random sample of the population.