Journal Article10.1016/J.BSE.2020.104166
Secondary metabolites produced by mangrove endophytic fungus Aspergillus fumigatus HQD24 with immunosuppressive activity
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TL;DR: Immunosuppressive activity guided chemical investigation, four alkaloids and eight polyketides were isolated from mangrove-derived Aspergillus fumigatus HQD24 and their structures were elucidated unambiguously based on the comprehensive spectroscopic analysis and comparison with literature data.
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About: This article is published in Biochemical Systematics and Ecology. The article was published on 01 Dec 2020. The article focuses on the topics: Aspergillus fumigatus & Plant use of endophytic fungi in defense.
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Applications of endophytic microbes in agriculture, biotechnology, medicine, and beyond.
TL;DR: In this article, the authors comprehensively review current and potential applications of endophytes in the agricultural, pharmaceutical, and industrial sectors, and briefly discuss the research objectives that should be focused upon in the coming years in order for endophyte and their metabolites to be fully harnessed for potential use in diverse areas.
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The endophytic Aspergillus strains: A bountiful source of natural products
TL;DR: This review covers the literature of the year 2020, reporting the isolation of 202 compounds obtained from more than 10 different endophytic Aspergillus species associated with different host plants, which exhibited diverse biological activities such as antibacterial, anti-cancer, anti‐plasmodial,Anti‐inflammatory, antioxidant, immunosuppressive and antifungal activities.
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Fungal Endophytes: Microfactories of Novel Bioactive Compounds with Therapeutic Interventions; A Comprehensive Review on the Biotechnological Developments in the Field of Fungal Endophytic Biology over the Last Decade
Aditi Gupta,Vineet Meshram,Mahiti Gupta,Soniya Goyal,K A Qureshi,Mariusz Jaremko,Kamlesh Kumar Shukla +6 more
TL;DR: In this paper , a systematic approach focuses on elucidating the origins of endophytic fungi, exploring the structural diversity and biological activities exhibited by these compounds, and giving special emphasis to the pharmacological activities and mechanism of action of certain compounds.
Biotechnological potential of fungi from a mangrove ecosystem: Enzymes, salt tolerance and decolorization of a real textile effluent
01 Jan 2022
TL;DR: In this article , the biotechnological potential of fungi from a mangrove ecosystem was evaluated using morphological and molecular analyses, which showed a predominance of hydrolytic enzymes and fungal tolerance to ≤ 50 g L-1 sodium chloride (NaCl) concentration, a sign of adaptive halophilia.
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Alkaloids from endophytic fungus Aspergillus fumigatus HQD24 isolated from the Chinese mangrove plant Rhizophora mucronata.
TL;DR: In this article, a chemical investigation of endophytic fungus Aspergillus fumigatus HQD24, isolated from the flower of Rhizophora mucronata, led to the isolation of eight alkaloids, including pyripyropene A (1), 1,11-dideacetyl-pyriropyropen A (2), pyriropene E (3), chaetominine (4), tryptoquivaline J (5), fumitremorgin C (6), 1-acetylβ-
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References
Phylogeny, identification and nomenclature of the genus Aspergillus
Robert A. Samson,Cobus M. Visagie,Jos Houbraken,Seung-Beom Hong,Vit Hubka,Corné H. W. Klaassen,Giancarlo Perrone,Keith A. Seifert,Antonia Susca,Joey B. Tanney,József Varga,Sándor Kocsubé,Gyöngyi Szigeti,Takashi Yaguchi,Jens Christian Frisvad +14 more
TL;DR: New combinations for accepted species presently lacking an Aspergillus name are introduced and an updated accepted species list for the genus is provided, now containing 339 species.
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The use of secondary metabolite profiling in chemotaxonomy of filamentous fungi.
TL;DR: Fungal chemotaxonomy based on secondary metabolites has been used successfully in large ascomycete genera such as Alternaria, Aspergillus, Fusarium, Hypoxylon, Penicillium, Stachybotrys, Xylaria and in few basidiomyceteGenera, but not in Zygomycota and ChytridiomyCota.
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Aspergillus fumigatus CY018, an endophytic fungus in Cynodon dactylon as a versatile producer of new and bioactive metabolites.
TL;DR: Aspergillus fumigatus CY018 was recognized as an endophytic fungus for the first time in the leaf of Cynodon dactylon and the EtOAc extract of a solid-matrix steady culture of this fungus afforded two new metabolites, named as perfumoid and asperfumin, together with six known bioactive compounds.
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Cytotoxic Alkaloids and Antibiotic Nordammarane Triterpenoids from the Marine-Derived Fungus Aspergillus sydowi
TL;DR: Three new diketopiperazine alkaloids, 6-methoxyspirotry Prostatin B, 18-oxotryprostatin A, and 14-hydroxyterezine D, as well as 12 known compounds, were isolated from the ethyl acetate extract of a marine-derived fungal strain, Aspergillus sydowi PFW1-13, by comprehensive spectroscopic analysis.
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Antiosteoporotic Activity of Anthraquinones from Morinda officinalis on Osteoblasts and Osteoclasts
Yan-Bin Wu,Cheng-Jian Zheng,Lu-Ping Qin,Lian-Na Sun,Ting Han,Lei Jiao,Qiao-Yan Zhang,Jin-Zhong Wu +7 more
TL;DR: Bioactivity-guided fractionation led to the successful isolation of antiosteoporotic components of M. officinalis and its anthraquinones that suggest therapeutic potential against osteoporosis.
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