Journal Article10.1136/adc.63.8.989-a
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D. Isaacs,E. R. Moxon,D. Harvey +2 more
- 01 Aug 1988
Vol. 63, pp 989-990
TL;DR: The provided text describes the treatment of respiratory syncytial virus infection and its effectiveness in immunocompromised individuals.
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Abstract: with severe respiratory syncytial virus infection. Crit Care Med 1987;15:1051-4. 13 Gelfand EW, McCurdy D, Pandu Rao C, Middleton PJ. Ribavirin treatment of viral pneumonitis in severe combined immunodeficiency disease. Lancet 1983;ii:732-3. 14 McIntosh K, Kurachek SC, Cairns LM, Burns JC, Goodspeed B. Treatment of respiratory viral infection in an immunodeficient infant with ribavirin aerosol. Am J Dis Child 1984;138: 305-8. 15 McMillan JA, Tristram DA, Weiner LB, et al. Prediction of the duration of hospitalization in patients with respiratory syncytial virus infection: use of clinical parameters. Pediatrics 1988;81: 22-6. 16 Wyde PR, Wilson SZ, Petrella R, Gilbert BE. Efficacy of highdose-short duration ribavirin aerosol treatment of respiratory syncytial virus infected cotton rats and influenza B virus infected mice. Antiviral Res 1987;7:211-20. 7 Isaacs D. Ribavirin. Pediatrics 1987;79:289-91.
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References
Aerosolized ribavirin treatment of respiratory syncytial virus infection in infants hospitalized during an epidemic.
TL;DR: The experince with ribavirin therapy during a major epidemic confirms and extends the results of previous controlled evaluations demonstrating this treatment safe and effective in high risk and seriously ill infants with RSV bronchiolitis and bronchopneumonia.