Recent developments in guanylating agents
TL;DR: An overview of recent advances in the development of guanylating reagents, which are defined as compounds forming a guanidine structure by a chemical transformation, is summarized.
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Abstract: Guanidines are important molecules with a wide range of interesting properties. In this overview we summarize recent advances in the development of guanylating reagents which we define as compounds forming a guanidine structure by a chemical transformation. We cover important classes of guanylating agents developed in the last two decades and representative examples are reported.
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Citations
The chemistry and biology of organic guanidine derivatives
TL;DR: The literature survey includes purely synthetic Guanidine derivatives, guanidine alkaloids and non-ribosomal peptides from bacteria and cyanobacteria, as well as related compounds isolated from marine and terrestrial invertebrates and higher plants.
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Guanidines: from classical approaches to efficient catalytic syntheses
TL;DR: This review focuses on the metal-mediated catalytic addition of amines to carbodiimides as an atom-economical alternative to the classical synthesis.
191
Biological activities of guanidine compounds.
TL;DR: Recent achievements in the synthesis of guanidine-containing molecules with diverse chemical, biochemical and pharmacological properties make them of great importance to the design and development of novel drugs acting at CNS, anti-inflammatory agents, inhibitors of Na+/H+ exchanger, inhibitor of NO synthase, antithrombotic, antidiabetic and chemotherapeutic agents as well as guanidinium-based transporters and vectors.
159
Recent development of synthetic preparation methods for guanidines via transition metal catalysis
TL;DR: Three aspects are included: transition-metal-catalyzed guanidine synthesis based on classical methods; catalytic guanylation reaction of amines with carbodiimides; and tandem catalyticGuanidines reactions.
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References
•Book
Solid-Phase Organic Synthesis
Kevin Burgess
- 14 Dec 1999
TL;DR: Solid Phase Synthesis of Guanidines (K. Burgess et al. as mentioned in this paper ) is a well-known line of research in solid phase organic synthesis, which is used for synthesis of natural products.
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