Journal Article10.2217/NNM-2021-0104
Quantum dots as a theranostic approach in Alzheimer's disease: a systematic review.
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TL;DR: A comprehensive literature search was conducted in PubMed and Google Scholar databases that included the following search terms: 'quantum dots', 'blood-brain barrier', 'cytotoxicity', 'toxicity' and 'Alzheimer's disease'; PRISMA guidelines were adhered to.
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About: This article is published in Nanomedicine: Nanotechnology, Biology and Medicine. The article was published on 28 Jun 2021.
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TL;DR: In this paper , a glutathione modified quantum dot (GSH-CdTe QDs) was synthesized and applied in a "turn-off" fluorescence probe to detect Cu2+.
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Congo Red-Derived Carbon Dots: Simultaneously as Fluorescence Probe for Protein Aggregates, Inhibitor for Protein Aggregation, and Scavenger of Free Radicals.
TL;DR: Wang et al. as discussed by the authors used Congo red (CR), a classical staining reagent with red fluorescence signal output for protein aggregates, to react with three different reductive carbon sources and ammonium persulfate to generate three CR-derived carbon dots (CDs).
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Recent advances in the effective removal of hazardous pollutants from wastewater by using nanomaterials—A review
Mamta Chahar,Sarita Khaturia,Harlal Singh,V.S. Solanki,Neha Agarwal,Dipak Kumar Sahoo,Virendra Kumar Yadav,Ashish Patel +7 more
TL;DR: This review explores the application of nanomaterials, including carbonaceous, metal-containing, and nanocomposites, in wastewater treatment, highlighting their potential for effective removal of hazardous pollutants and sustainable water decontamination.
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MoS2 quantum dots based on lipid drug delivery system for combined therapy against Alzheimer's disease
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TL;DR: In this paper , Molybdenum disulfide quantum dots (MoS2 QDs/lipid) were selected as carriers and functionalized with lipids to improve their dispersibility in water, while effectively escaping immune clearance.
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References
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
TL;DR: Moher et al. as mentioned in this paper introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses, which is used in this paper.
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
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NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
Clifford R. Jack,David A. Bennett,Kaj Blennow,Maria C. Carrillo,Billy Dunn,Samantha Budd Haeberlein,David M. Holtzman,William J. Jagust,Frank Jessen,Jason Karlawish,Enchi Liu,José Luis Molinuevo,Thomas J. Montine,Creighton H. Phelps,Katherine P. Rankin,Christopher C. Rowe,Philip Scheltens,Eric Siemers,Heather M. Snyder,Reisa A. Sperling,Cerise L Elliott,Eliezer Masliah,Laurie M. Ryan,Nina Silverberg +23 more
TL;DR: This research framework seeks to create a common language with which investigators can generate and test hypotheses about the interactions among different pathologic processes (denoted by biomarkers) and cognitive symptoms and envision that defining AD as a biological construct will enable a more accurate characterization and understanding of the sequence of events that lead to cognitive impairment that is associated with AD.
Understanding biophysicochemical interactions at the nano–bio interface
Andre E. Nel,Lutz Mädler,Darrell Velegol,Tian Xia,Eric M.V. Hoek,Ponisseril Somasundaran,Fred Klaessig,Vince Castranova,Mike Thompson +8 more
TL;DR: Probing the various interfaces of nanoparticle/biological interfaces allows the development of predictive relationships between structure and activity that are determined by nanomaterial properties such as size, shape, surface chemistry, roughness and surface coatings.
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Astrocyte–endothelial interactions at the blood–brain barrier
TL;DR: Specific interactions between the brain endothelium, astrocytes and neurons that may regulate blood–brain barrier function are explored to lead to the development of new protective and restorative therapies.
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