Patent
Quantitative microfluidic devices
Jason P. Rolland,Patrick Beattie,Shailendra Kumar,Sidhartha Jain +3 more
- 27 Sep 2012
17
TL;DR: Paper-based assay devices for detection and quantification of analytes in liquid clinical samples, e.g., blood or urine, have been proposed in this paper for use in regions of the world where health care infrastructure is absent.
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Abstract: Described herein are disposable paper-based assay devices for detection and quantitation of analytes in liquid clinical samples, e.g., blood or urine. The devices may be particularly suitable for use in regions of the world where health care infrastructure is absent. The test devices are versatile in that they can be adapted to detect a variety of analytes. The devices are also easy to use and interpret. Typically, all that is needed to conduct an assay is to apply a drop of sample to the indicated location on the device. The devices are typically colorimetric and readable with the naked eye.
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Citations
Patent
Bipolar electrode electrogenerated chemiluminescence paper based micro-fluidic chip and imaging sensing application thereof
Zhang Chunsun,Liu Rui +1 more
- 10 Dec 2014
TL;DR: In this paper, a bipolar electrode electrogenerated chemiluminescence paper based micro-fluidic chip and the application thereof to imaging sensing was disclosed, and the chip has the advantages of bipolar electrode electrochemistry and paper-based microfluidics.
11
Patent
Instrument-free quantitative analysis method for fast detecting test paper, and application of instrument-free quantitative analysis method
Zhang Yun,Nie Jinfang,Tan Jufu,Li Jingxian,Zhang Ju +4 more
- 17 Dec 2014
TL;DR: In this article, an instrument-free quantitative analysis method for fast detecting test paper, and application of the instrument free quantitative analyte method was presented. But the method was not applied to quantitative detection on target analytes in various liquid samples of urine, blood, serum, saliva, water etc.
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Patent
Robust colorimetric processing method for paper based sensors
Jing Zhou,Nancy Y. Jia,Wei Hong,Mandakini Kanungo,Xing Liu +4 more
- 15 Jul 2015
TL;DR: In this article, a colorimetric method that couples sensor design with image processing to enable automated evaluation of test results obtained by paper-based sensors is proposed, which can match ink color and dye used in colourimetric reaction in terms of their absorption in spectral range (e.g., red, green, blue).
5
Patent
Paper sensing and analytic service workflow methods and systems
Nancy Y. Jia,Mandakini Kanungo,Wei Hong,Jing Zhou +3 more
- 13 Aug 2015
TL;DR: In this paper, a workflow method and system associated with a paper-based sensor is described. But, the paper sensor is used to collect data from a test material, such as, but not limited to, blood, to the paper based sensor.
4
Patent
Design of paper sensor
Wei Hong,Jing Zhou,Mandakini Kanungo,Xing Liu,Nancy Y. Jia,Vella Sara Dzh,Lu Laura +6 more
- 15 Jul 2015
TL;DR: In this paper, the authors proposed a biomedical paper sensor which can determine the concentration of biological materials in fluids such as blood, urine, and saliva using a plurality of axially radiating test zones.
4
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Paper-Based ELISA
Chao-Min Cheng,Andres W. Martinez,Jinlong Gong,Charles R. Mace,Scott T. Phillips,Emanuel Carrilho,Emanuel Carrilho,Katherine A. Mirica,George M. Whitesides +8 more
TL;DR: It is established that P-ELISA can be used to detect and quantify antibodies to the HIV-1 envelope antigen gp41 in human serum using an anti-human IgG antibody conjugated to alkaline phosphatase (ALP) to produce a colorimetric readout.
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Patent
Lateral Flow and Flow-through Bioassay Devices Based on Patterned Porous Media, Methods of Making Same, and Methods of Using Same
George M. Whitesides,Scott T. Phillips,Andres W. Martinez,Manish J. Butte,Amy P. Wong,Samuel W. Thomas,Hayat Sindi,Sarah J. Vella,Emanuel Carrilho,Katherine A. Mirica,Yanyan Liu +10 more
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TL;DR: In this article, the authors provide lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same, which include a porous, hydrophilic medium; a fluid impervious barrier comprising polymerized photoresist.
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Paper as a novel material platform for devices
TL;DR: An overview of paper’s unique properties and how these properties lead to a potential for changing the integrated microfluidic and flexible electronics landscape and a brief outlook on the future of this emerging field.
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Patent
Three-dimensional microfluidic devices
Emanuel Carrilho,Andres W. Martinez,Katherine A. Mirica,Scott T. Phillips,Adam C. Siegel,Benjamin J. Wiley,George M. Whitesides +6 more
- 27 Mar 2009
TL;DR: In this article, a plurality of patterned porous, hydrophilic layers and a fluid-impermeable layer disposed between every two adjacent patterned porosity, hydophilic layers are described.
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