Quantifying size-dependent interactions between fluorescently labeled polystyrene nanoparticles and mammalian cells
Juan A. Varela,Mariana G. Bexiga,Mariana G. Bexiga,Christoffer Åberg,Jeremy C. Simpson,Kenneth A. Dawson +5 more
TL;DR: A comparison of the uptake rates of fluorescently labeled carboxylated polystyrene NPs of different sizes in two different cell types shows that 40 nm NPs are internalized faster than 20 nm or 100 nm particles in both cell lines studied, suggesting that there is a privileged size gap in which the internalization of NPs is higher.
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Abstract: Background
Nanoparticles (NPs) are currently used in a wide variety of fields such as technology, medicine and industry. Due to the novelty of these applications and to ensure their success, a precise characterization of the interactions between NPs and cells is essential.
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Citations
Engineered nanoparticles interacting with cells: size matters
TL;DR: Common techniques to characterize NP size are summarized, recent work on the impact of NP size on active and passive cellular internalization and intracellular localization are highlighted and Cytotoxic effects are discussed.
Emergence of Nanoplastic in the Environment and Possible Impact on Human Health
TL;DR: The influence of particle size and surface chemistry are discussed, in order to understand the possible risks of nanoplastics for humans and provide recommendations for future studies.
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C. Della Torre,Elisa Bergami,Anna Salvati,Claudia Faleri,Paola Cirino,Kenneth A. Dawson,Ilaria Corsi +6 more
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Impact of Microplastics and Nanoplastics on Human Health
Maxine Swee-Li Yee,Ling-Wei Hii,Chin King Looi,Wei-Meng Lim,Shew Fung Wong,Yih-Yih Kok,Yih-Yih Kok,Boon-Keat Tan,Chiew Yen Wong,Chiew Yen Wong,Chee-Onn Leong +10 more
TL;DR: In this article, the potential of how nano-plastics move through the gut, lungs and skin epithelia in causing systemic exposure has not been examined thoroughly, and a review explores thoroughly on how nanoplastics are created, how they behave/breakdown within the environment, levels of toxicity and pollution of these nanoplastic, and the possible health impacts on humans, as well as suggestions for additional research.
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Micro- and Nano-plastics and Human Health
Tamara S. Galloway
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TL;DR: The potential for microplastics and nanoplastics of environmental origin to cause harm to human health remains understudied, and some of the most widely encountered plastics in everyday use are identified and their potential hazards listed.
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