Predictors of stroke in patients undergoing cardiac surgery
Handerson Nunes dos Santos,Ellen Hettwer Magedanz,João Carlos Vieira da Costa Guaragna,Natalia Nunes dos Santos,Luciano Cabral Albuquerque,Marco Antônio Goldani,João Batista Petracco,Luiz Carlos Bodanese,Luiz Carlos Bodanese +8 more
TL;DR: The study identified the following risk predictors for stroke after cardiac surgery: age, urgent and emergency surgery, aortic valve disease, History of atrial fibrillation, peripheral artery disease, history of cerebrovascular disease and cardiopulmonary bypass time > 110 minutes.
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Abstract: Objective: To determine the risk factors related to the development of stroke in patients undergoing cardiac surgery. Methods: A historical cohort study. We included 4626 patients aged > 18 years who underwent coronary artery bypass surgery, heart valve replacement surgery alone or heart valve surgery combined with coronary artery bypass grafting between January 1996 and December 2011. The relationship between risk predictors and stroke was assessed by logistic regression model with a significance level of 0.05. Results: The incidence of stroke was 3% in the overall sample. After logistic regression, the following risk predictors for stroke were found: age 50-65 years (OR=2.11 - 95% CI 1.05-4.23 - P=0.036) and age >66 years (OR=3.22 - 95% CI 1.6-6.47 - P=0.001), urgent and emergency surgery (OR=2.03 - 95% CI 1.20-3.45 - P=0.008), aortic valve disease (OR=2.32 - 95% CI 1.18-4.56 - P=0.014), history of atrial fibrillation (OR=1.88 - 95% CI 1.05-3.34 - P=0.032), peripheral artery disease (OR=1.81 - 95% CI 1.13-2.92 - P=0.014), history of cerebrovascular disease (OR=3.42 - 95% CI 2.19-5.35 - P 110 minutes (OR=1.71 - 95% CI 1.16-2.53 - P=0.007). Mortality was 31.9% in the stroke group and 8.5% in the control group (OR=5.06 - 95% CI 3.5-7.33 - P 110 minutes.
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Citations
Atrial Fibrillation After Cardiac Surgery: Clinical Update on Mechanisms and Prophylactic Strategies
Jesse Raiten,Kamrouz Ghadimi,John G.T. Augoustides,Harish Ramakrishna,Prakash A. Patel,Stuart J. Weiss,Jacob T. Gutsche +6 more
TL;DR: An expert review of the incidence, pathogenesis, and preventative strategies for AF after cardiac surgery highlights the need for more thorough understanding of the mechanisms underlying the genesis of AF in this setting.
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Predictors and Outcomes of Ischemic Stroke After Cardiac Surgery.
Ibrahim Sultan,Valentino Bianco,Arman Kilic,Tudor G Jovin,Ashutosh P Jadhav,Brian T. Jankowitz,Edgar Aranda-Michel,Michael P D’Angelo,Forozan Navid,Yisi Wang,Floyd Thoma,Thomas G. Gleason +11 more
TL;DR: Stroke with LVO was associated with worse survival, however, early intervention did not impart a survival benefit and predictors of stroke included increasing age, known cerebrovascular disease, diabetes, and emergent operative status.
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Role of long noncoding RNA MEG3/miR-378/GRB2 axis in neuronal autophagy and neurological functional impairment in ischemic stroke.
TL;DR: Findings suggested that miR-378 might protect against neuronal autophagy and neurological functional impairment and proposed that a MEG3/miR- 378/GRB2 regulatory axis contributed to better understanding of the pathophysiology of ischemic stroke.
42
Predictors of stroke in patients undergoing cardiac surgery
Handerson Nunes dos Santos,Ellen Hettwer Magedanz,João Carlos Vieira da Costa Guaragna,Natalia Nunes dos Santos,Luciano Cabral Albuquerque,Marco Antônio Goldani,João Batista Petracco,Luiz Carlos Bodanese,Luiz Carlos Bodanese +8 more
TL;DR: The study identified the following risk predictors for stroke after cardiac surgery: age, urgent and emergency surgery, aortic valve disease, History of atrial fibrillation, peripheral artery disease, history of cerebrovascular disease and cardiopulmonary bypass time > 110 minutes.
Use of EuroSCORE as a predictor of morbidity after cardiac surgery
TL;DR: The EuroSCORE proved to be applicable in the prediction of major postoperative morbidities in cardiac surgery: respiratory tract infection and renal failure dialitic, with proper calibration and good discrimination.
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