Pre-Gestational Consumption of Ultra-Processed Foods and Risk of Gestational Diabetes in a Mediterranean Cohort. The SUN Project.
Alessandro Leone,Miguel Ángel Martínez-González,Winston J. Craig,Ujué Fresán,Clara Gómez-Donoso,Maira Bes-Rastrollo +5 more
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TL;DR: In this article, the authors investigated the relationship between the pre-gestational consumption of ultraprocessed foods (UPF) and the risk of gestational diabetes (GDM).
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Abstract: We aimed to investigate the relationship between the pre-gestational consumption of ultra-processed foods (UPF) and the risk of gestational diabetes (GDM). We carried out a prospective study among 3730 Spanish women of the SUN cohort who reported at least one pregnancy after baseline recruitment. Cases of GDM were identified among women with a confirmed diagnosis of GDM. UPF consumption was assessed through a validated, semi-quantitative food frequency questionnaire and the frequency of UPF consumption was categorized in tertiles. We identified 186 cases of GDM. In the pooled sample, we did not observe a significant association of UPF with the risk of GDM. When we stratified by age, the multivariate OR for the third tertile of UPF consumption compared with the lowest one was 2.05 (95% CI 1.03, 4.07) in women aged ≥30 years at baseline (Ptrend = 0.041). The association remained significant in a sensitivity analysis after changing many of our assumptions and adjusting for additional confounders. No association between a higher UPF consumption and GDM risk was observed in women aged 18–29 years. The pre-gestational UPF consumption may be a risk factor for GDM, especially in women aged 30 years or more. Confirmatory studies are needed to validate these findings.
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Citations
Ultra-processed foods and human health: from epidemiological evidence to mechanistic insights.
Bernard Srour,Melissa C. Kordahi,Erica Bonazzi,Mélanie Deschasaux-Tanguy,Mathilde Touvier,Benoit Chassaing +5 more
TL;DR: In this article , an overview of the current data that highlight an association between ultra-processed food consumption and various chronic diseases, with a focus on epidemiological evidence and mechanistic insights involving the intestinal microbiota.
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Ultra-processed foods and obesity and adiposity parameters among children and adolescents: a systematic review
Ramona De Amicis,S. Mambrini,Marta Pellizzari,Andrea Foppiani,Simona Bertoli,Alberto Battezzati,Alessandro Leone +6 more
TL;DR: In this article , the association between the consumption of ultra-processed foods and obesity and adiposity measurements has been established in adults, but the situation remains unclear in children and adolescents.
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Ultra-processed foods and cardiometabolic health: public health policies to reduce consumption cannot wait
Mathilde Touvier,Maria Laura da Costa Louzada,Dariush Mozaffarian,Phillip Baker,Filippa Juul,Bernard Srour +5 more
TL;DR: Ultra-processed foods and cardiometabolic health: Public health policies to reduce consumption are urgently needed due to the incomplete understanding of the mechanisms underlying the link.
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Ultra-processed foods and health: a comprehensive review.
Yin Zhang,Edward Giovannucci +1 more
TL;DR: This manuscript provides a comprehensive review of trends in global consumption of ultra-processed foods, dietary nutrient profile ofUltra-processing foods, demographic, socioeconomic, psychological, and behavioral characteristics of ultra -processed food consumers, current evidence from longitudinal studies at the population level on the association between ultra- Processed foods consumption and major health outcomes, and potential mechanisms linking ultra- processed foods with these outcomes.
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Ultra-Processed Food Consumption and Incidence of Obesity and Cardiometabolic Risk Factors in Adults: A Systematic Review of Prospective Studies
S. Mambrini,Simone Ravella,Marta Pellizzari,Ramona De Amicis,Andrea Foppiani,Alberto Battezzati,Simona Bertoli,Alessandro Leone +7 more
TL;DR: In this article , the authors conducted a systematic review of prospective studies from PubMed and Web of Science investigating the association between UPF consumption and the incidence of obesity and cardiometabolic risk factors.
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