Journal Article10.1097/INF.0B013E3182A14971
Population-based Incidence of Invasive Haemophilus influenzae and Pneumococcal Diseases Before the Introduction of Vaccines in Japan
Riko Nakamura,Takehiro Togashi +1 more
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TL;DR: Before the introduction of vaccines, the incidence of bacterial meningitis among children aged 28 days to 5 years was 8.48, Haemophilus influenzae type-b meningiti was 5.65 and Streptococcus pneumoniaeMeningitis was 1.85 per 100,000 person-years in Hokkaido, Japan.
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Abstract: Before the introduction of vaccines, the incidence of bacterial meningitis among children aged 28 days to 5 years was 848, Haemophilus influenzae type-b meningitis was 565 and Streptococcus pneumoniae meningitis was 185 per 100,000 person-years in Hokkaido, Japan The incidence of bacteremia caus
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Citations
Invasive Haemophilus influenzae Infections after 3 Decades of Hib Protein Conjugate Vaccine Use.
TL;DR: A comprehensive and critical overview of the current global epidemiology of invasive H. influenzae infections in different geographic regions of the world can be found in this paper, where the authors discuss those now at risk of invasive Hib disease, describes the emergence of other severe invasive infections, and emphasizes the importance of long-term, comprehensive, clinical and microbiologic surveillance to monitor a vaccine's impact.
Genetic Determinants of Tetracycline Resistance in Clinical Streptococcus pneumoniae Serotype 1 Isolates from Niger.
TL;DR: Clinical Streptococcus pneumoniae type 1 isolated during 2002 to 2009 meningitis surveillance in Niger were fully susceptible to macrolides and quinolones but highly resistant to tetracycline (77.4%) through acquisition of a defective Tn5253 like element composed of Tn 5252 and Tn916 transposons.
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Characteristics and Risk Factors of Late-onset Bloodstream Infection Beyond 6 Months After Liver Transplantation in Children.
TL;DR: Late-onset BSI developed in 9% of recipients after pediatric LT, associated with increased retransplantation rate, mortality and mortality and Gram-negative rods accounted for the majority of late-onsET BSI as a consequence of abdominal infection, but the focus was often unclear.
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Immunogenicity and safety of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) co-administered with DTPa vaccine in Japanese children: A randomized, controlled study
Satoshi Iwata,Naohisa Kawamura,Haruo Kuroki,Yasunobu Tokoeda,Mitsunobu Miyazu,Asayuki Iwai,Tomohiro Oishi,Tomohide Sato,Akari Suyama,Nancy François,Fakrudeen Shafi,Javier Ruiz-Guiñazú,Dorota Borys +12 more
TL;DR: In conclusion, PHiD-CV induced robust immune responses and was well tolerated when co-administered with DTPa in a 3-dose priming plus booster regimen to Japanese children.
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Rare Cases of Pseudomonas aeruginosa Meningitis in Children: 10-Year Experience in a Single Center.
Lijun Liu,Lvchang Zhu,Chanchan Hu,Shuzhen Zhu +3 more
TL;DR: Rare cases of Pseudomonas aeruginosa meningitis in children with high mortality rate. Patients with leukemia or neurosurgical procedures are at highest risk.
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TL;DR: Six infants with Kawasaki disease had lower motor neuron facial palsy of acute onset and improved within two months and four infants had central nervous system involvement with remarkable changes of cerebrum during an acute stage, and these findings disappeared completely within six months.
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Cerebrospinal fluid profile in patients with acute Kawasaki disease.
Laura D. Dengler,Edmund V. Capparelli,John F. Bastian,David J. Bradley,Mary P. Glode,Sandra Santa,Jane W. Newburger,Annette L. Baker,Tomoyo Matsubara,Jane C. Burns +9 more
TL;DR: In the present series approximately one-third of KD patients who underwent an LP had CSF pleocytosis with a mononuclear cell predominance, and no patient had significant hypoglycorrhachia, and elevation of the CSF protein was uncommon.
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Concomitant Respiratory Viral Infections in Children with Kawasaki Disease
TL;DR: It was shown that 8.8% of patients with KD had documented respiratory viral infections and patients with concomitant viral infections had a higher frequency of coronary artery dilatations and were significantly more often diagnosed with incomplete KD.
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Global reduction of Hib disease: what are the next steps? Proceedings of the meeting: Scottsdale, Arizona, September 22-25, 2002
TL;DR: This supplement is a synthesis of the major themes and key lessons identified at the meeting to discuss the epidemiology and control of disease caused by Haemophilus influenzae type b (Hib) in the era of Hib conjugate vaccines.
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