Journal Article10.1016/0014-4894(87)90179-2
Pneumocystis carinii: immunoblotting and immunofluorescent analyses of serum antibodies during experimental rat infection and recovery.
Peter D. Walzer,Peter D. Walzer,David Stanforth,David Stanforth,Michael J. Linke,Michael J. Linke,Melanie T. Cushion,Melanie T. Cushion +7 more
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TL;DR: Serum antibodies to Pneumocystis carinii were measured in rats by the indirect fluorescent antibody and immunoblotting techniques and identified bands of 45, 50, and 116 kDa as the major reactive moieties of P.carinii.
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About: This article is published in Experimental Parasitology. The article was published on 01 Jun 1987. The article focuses on the topics: Pneumocystis carinii & Serology.
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Citations
Serologic Responses to Pneumocystis carinii Antigens in Health and Disease
S. L. Peglow,A. G. Smulian,A. G. Smulian,A. G. Smulian,M. J. Linke,M. J. Linke,M. J. Linke,C. L. Pogue,C. L. Pogue,C. L. Pogue,S. Nurre,S. Nurre,S. Nurre,J. Crisler,J. Crisler,J. Crisler,John P. Phair,J. W. M. Gold,J. W. M. Gold,J. W. M. Gold,D. Armstrong,D. Armstrong,D. Armstrong,Peter D. Walzer,Peter D. Walzer,Peter D. Walzer +25 more
TL;DR: The data suggest that the 40-kDa antigen is a major marker of P. carinii infection and that immunoblotting is useful in measuring serum antibody responses to the organism in both normal and immunocompromised hosts.
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Immunoblotting and dot blotting
TL;DR: A variety of methods has been available for many years for the analytical separation of mixtures of proteins into their component parts by electrophoresis in a gel, usually agarose or polyacrylamide.
188
Prevention and treatment of pneumocystis pneumonia.
TL;DR: The number of cases of Pneumocystis carinii pneumonia recognized per year in the United States has increased dramatically, from about 65 in 1967 through 1970 to an estimated 20,000 to 60,000 in the late 1980s and early 1990s, largely due to the epidemic of the acquired immunodeficiency syndrome (AIDS).
188
Translocation of surface antigen genes to a unique telomeric expression site in Pneumocystis carinii.
TL;DR: It is shown that the UCS was present in one copy per haploid genome, but that different MSG genes were linked to the unique UCS locus in different members of a P. c.
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Outbreaks of Pneumocystis carinii pneumonia in colonies of immunodeficient mice.
Peter D. Walzer,C K Kim,Michael J. Linke,C L Pogue,Michael J Huerkamp,C E Chrisp,A V Lerro,S K Wixson,E Hall,L D Shultz +9 more
TL;DR: Pneumocystis carinii pneumonia occurred in colonies of mice at four different institutions as discussed by the authors, which was characterized by chronic wasting and respiratory insufficiency in older mice and in animals housed in cages with special protective tops.
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TL;DR: A study of 194 patients with confirmed Pneumocystis cariniipneumonia in the United States during a 3-year period showed that P. cariniIPneumonia occurred almost exclusively in the immunosuppre...
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