Percutaneous replacement of pulmonary valve in a right-ventricle to pulmonary-artery prosthetic conduit with valve dysfunction

TL;DR: Nonsurgical implantation of a prosthetic heart valve can be successfully achieved with immediate and midterm hemodynamic and clinical improvement, and PHV might become an important therapeutic alternative for the treatment of selected patients with nonsurgical aortic stenosis.

TL;DR: Experts in the field are selected and undertake a comprehensive review of the published evidence for management and/or prevention of a given condition, including assessment of the risk–benefit ratio.

TL;DR: In this paper, the use of diagnostic procedures and therapies introduced and tested for detection, management, or prevention of disease is discussed. But, the focus is on the medical profession.

TL;DR: Despite gradual deterioration of homograft conduits, they remain an important tool in the correction of many complex lesions with excellent 15-year patient survival and when patient survival was considered, patients operated on more recently survived longer despite the fact that their conduits were being replaced earlier.

TL;DR: Stent implantation in obstructed RV-PA conduits results in significant immediate hemodynamic and angiographic improvement and extends conduit life span by several years and increases the interval between conduit reoperations.

TL;DR: The poor performance of porcine-valved tightly woven Dacron conduits warrants a change to use of an alternative conduit, particularly in smaller children, and possible alternatives include antibiotic-sterilized homografts and valved or nonvalved high-porosity knitted Dacrons appropriately pretreated with collagen impregnation or fibrin glue.

TL;DR: Assessment of the impact of implantation of balloon-expandable stents on right ventricular outflow obstruction in children with congenital heart disease supports the view that intravascular stenting will become an important adjunct in the management of children with defects.