Journal Article10.1007/S00059-019-04868-0
Percutaneous mitral valve repair in recurrent severe mitral valve regurgitation after mitral annuloplasty : MitraClip-in-the-ring as a complementary strategy.
Sven T. Pleger,Nicolas A. Geis,Michael M. Kreusser,Haitham Abu-Sharar,Christian Sebening,Gábor Szabó,Hugo A. Katus,Philip Raake +7 more
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TL;DR: MitraClip-in-the-ring is feasible and in principle safe for treating Carpentier type IIIb severe MV regurgitation after surgical MV repair using mitral annuloplasty and resulted in immediate amelioration of clinical symptoms and increased physical exercise capacity.
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Abstract: Patients with reduced left ventricular (LV) function undergoing coronary artery bypass graft surgery or/and aortic valve replacement occasionally show severe mitral valve (MV) regurgitation and thus also undergo surgical mitral annuloplasty. Over time, further deterioration of LV function and additional ischemic events cause recurrence of severe MV regurgitation due to the Carpentier IIIb morphology of the MV that is not adequately addressed by the previously implanted annuloplasty ring. Seven patients (Society of Thoracic Surgeons score: 7.5 ± 1.5%) with Carpentier type-IIIb recurrent severe MV regurgitation, having undergone prior cardiothoracic surgery (median: 40 months) including mitral annuloplasty, were treated with the MitraClip device. MitraClip implantation resulted in significantly reduced MV regurgitation and improved New York Heart Association functional state, translating into an increased exercise capability and improved cardiac biomarkers. The morphology of the MV was adequately addressed without causing relevant MV stenosis, while the MV annulus area remained unaltered. The procedure was safe with a 30-day mortality rate of 0%. MitraClip-in-the-ring is feasible and in principle safe for treating Carpentier type IIIb severe MV regurgitation after surgical MV repair using mitral annuloplasty. MitraClip-in-the-ring resulted in immediate amelioration of clinical symptoms and increased physical exercise capacity.
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Citations
Radiofrequency Ablation Alters the Microstructural Organization of Healthy and Enzymatically Digested Porcine Mitral Valves
TL;DR: Investigation of mechanisms by which radiofrequency ablation alters the geometry, microstructural organization, and mechanical properties of healthy and digested leaflets found this technique may be a therapeutic approach for myxomatous mitral valve disease.
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Long-term results of the edge-to-edge repair for failed mitral valve repair as a bailout option
TL;DR: There is a slowly progressive elevation of TMPG after E2E mitral repair, while mildly elevated TMPG can be tolerated in most patients, and in appropriate patients, the E 2E repair combined with annuloplasty provides an effective “bailout” choice.
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Erratum zu: Interventionelle Therapie von AV-Klappenerkrankungen – Kriterien für die Zertifizierung von Mitralklappenzentren. Positionspapier der Deutschen Gesellschaft für Kardiologie
Stephan Baldus,Ralph Stephan von Bardeleben,Holger Eggebrecht,A. Elsässer,Jörg Hausleiter,Hüseyin Ince,Malte Kelm,Karl-Heinz Kuck,E. Lubos,Holger Nef,Philip Raake,Andreas Rillig,Volker Rudolph,P. C. Schulze,Axel Schlitt,Christoph Stellbrink,Helge Möllmann +16 more
TL;DR: In der Legende der Abb. as mentioned in this paper, die Abkurzung „TMVR“ falsch aufgelost wurde die Abbildung mit der korrekten Legende. Wir bitten, diesen Fehler zu entschuldigen und die korrigierte …
Transcatheter Mitral Valve Repair for Failed Surgical Mitral Valve Repair: A Systematic Review and Meta-Analysis
TL;DR: Transcatheter mitral valve repair for failed initial surgical MVr was safe and effective, which should be recommended in selected patients if technically feasible, and follow-up survival was 94%.
Interventionelle Therapie von AV-Klappenerkrankungen – Kriterien für die Zertifizierung von Mitralklappenzentren
Stephan Baldus,Ralph Stephan von Bardeleben,Holger Eggebrecht,A. Elsässer,Jörg Hausleiter,Hüseyin Ince,Malte Kelm,Karl-Heinz Kuck,E. Lubos,Holger Nef,Philip Raake,Andreas Rillig,Volker Rudolph,P. C. Schulze,Axel Schlitt,Christoph Stellbrink,Helge Möllmann +16 more
TL;DR: Dieses Papier stellt die Ergebnisse aktueller Studien dar and gibt Empfehlungen zur Indikation interventioneller Behandlungsverfahren bei Mitral- and Trikuspidalklappeninsuffizienz.
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Guidelines on the management of valvular heart disease The Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology
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Transcatheter Mitral-Valve Repair in Patients with Heart Failure.
Gregg W. Stone,JoAnn Lindenfeld,William T. Abraham,Saibal Kar,D. Scott Lim,Jacob M. Mishell,Brian Whisenant,Paul A. Grayburn,Michael Rinaldi,Samir R. Kapadia,Vivek Rajagopal,Ian J. Sarembock,Andreas Brieke,Steven O. Marx,David J. Cohen,Neil J. Weissman,Michael J. Mack +16 more
TL;DR: Among patients with heart failure and moderate‐to‐severe or severe secondary mitral regurgitation who remained symptomatic despite the use of maximal doses of guideline‐directed medical therapy, transcatheter mitral‐valve repair resulted in a lower rate of hospitalization forHeart failure and lower all‐cause mortality within 24 months of follow‐up than medical therapy alone.
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