Book Chapter10.1016/B978-0-08-100803-4.00009-7
Peptide and protein printing for tissue regeneration and repair
J. Brinkmann,Jens Voskuhl,Pascal Jonkheijm +2 more
- 01 Jan 2018
- pp 229-243
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TL;DR: Most studies involving the signaling of focal adhesion complexes with surface-immobilized proteins have employed defined structures that were conveniently made by conventional microcontact printing.
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Abstract: Arrays of peptides and proteins play an important role in various areas of biomedical and biotechnological research that range from biomarker detection and proteomic screens to drug discovery Defined arrays of peptides and proteins also facilitate systemic understanding of culturing and studying cells on surfaces For example, cellular adhesion is a process mediated by the interaction of cell-surface receptors with ligands from the extracellular matrix, which results in the clustering of receptors into focal adhesion complexes This elaborate and highly regulated process is believed to play a significant role in many essential cellular functions Most studies involving the signaling of focal adhesion complexes with surface-immobilized proteins have employed defined structures that were conveniently made by conventional microcontact printing
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Present status of the functional advanced micro-, nano-printings – a mini review
TL;DR: A mini review of additive micro and nano printing techniques, including contact and noncontact, and roll to roll (R2R) printing methods as well as recently emerging techniques such as micro- or nano-pen printings, laser-induced forward transfer (LIFT) and aerosol jet printing (APJ), is presented in this paper.
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The Bumpy Road to Stem Cell Therapies: Rational Design of Surface Topographies to Dictate Stem Cell Mechanotransduction and Fate.
James Carthew,Jason Taylor,M. R. Garcia-Cruz,Nasim Kiaie,Nicolas H. Voelcker,Victor J. Cadarso,Jessica E. Frith +6 more
TL;DR: This review focuses on the challenges and opportunities in applying micro- and nanotopographies to dictate stem cell fate for regenerative medicine, including the current understanding of the mechanotransductive mechanisms by which these cues are interpreted by the cells, as well as the specific effects of surface topographies on cell differentiation and fate.
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Strategies for the enhancement of nail plate permeation of drugs to treat onychomycosis
TL;DR: The use of drugs and formulations with favourable characteristics such as small size, absence of lipophilicity, hydrophilic nature, hydrating properties, and appropriate pH can greatly improve permeation.
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