Penicillin as a chemotherapeutic agent

TL;DR: Doxycycline was very effective in the treatment of Staphylococcus aureus and Streptococcus beta haemolyticus infections.

TL;DR: The results indicate that AOM and AMS diagnoses in primary care are frequently based merely on symptoms and nonspecifi c clinical fi ndings, and criteria for diagnoses are often loose, and diagnostic equipment seldom used.

TL;DR: Sulphapyridine is an efficient prophylactic or therapeutic agent against intradermal infection with the strain of Vibrion septique selected for test, whereas, in intramuscular infection the drug is unreliable and saves only a relatively small proportion of animals.

TL;DR: A study has been made of the toxicity for dogs of a protein-free preparation of the bactericidal substance described by Dubos when injected by the intravenous route, and animals which received daily 0.2 mg/kg or less for 10 days showed only minor evidence of toxicity.

TL;DR: In 1929, Fleming observed that a mold which he identified as Penicillium rubrum (Biourge), but which more closely resembles Pencillium notatum (Westling) was able to produce a substance which inhibited the growth of certain bacteria.

TL;DR: It is shown that the bactericidal agent protects white mice against infection with large numbers of virulent pneumococci, and exerts a curative effect when administered to mice several hours after injection of the infecting organisms.