Journal Article10.1080/09205063.2017.1394711
PCL and PCL-based materials in biomedical applications
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TL;DR: PCL is a polyester that has been widely used in tissue engineering field for its availability, relatively inexpensive price and suitability for modification, and it can be used under harsh mechanical, physical and chemical conditions without significant loss of its properties.
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Abstract: Biodegradable polymers have met with an increasing demand in medical usage over the last decades. One of such polymers is poly(e-caprolactone) (PCL), which is a polyester that has been widely used in tissue engineering field for its availability, relatively inexpensive price and suitability for modification. Its chemical and biological properties, physicochemical state, degradability and mechanical strength can be adjusted, and therefore, it can be used under harsh mechanical, physical and chemical conditions without significant loss of its properties. Degradation time of PCL is quite long, thus it is used mainly in the replacement of hard tissues in the body where healing also takes an extended period of time. It is also used at load-bearing tissues of the body by enhancing its stiffness. However, due to its tailorability, use of PCL is not restricted to one type of tissue and it can be extended to engineering of soft tissues by decreasing its molecular weight and degradation time. This review ou...
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Citations
Screening and efficient production of engineered lipase B from Candida Antarctica for eco-friendly recycling of waste polycaprolactone
01 Jan 2022
TL;DR: In this article , the authors developed a screening and extracellular production system for a PCL-depolymerizing enzyme with high catalytic activity that can produce large quantities of the enzyme with a relatively simple purification step.
5
Thermal Property Control by Copolymerization of Trimethylene Carbonate and Its Derivative Bearing Triphenylmethyl Group
TL;DR: In this paper , the copolymers of TMC and TrTMC derivatives were obtained by varying the feeding ratio of their monomers with good yields as hexane-isopropanol (9/1, v/v) insoluble part.
4
Trimethoxysilyl end-capped hyperbranched polyglycidol/polycaprolactone copolymers for cell delivery and tissue repair: synthesis, characterisation and aqueous solution properties
Clara González-Chomón,Vasil M. Garamus,Stanislav Rangelov,John R. Ebdon,Christo P. Novakov,Silvia S. Halacheva +5 more
TL;DR: In this paper, the effect of copolymer composition and structure upon the crystallization, melting, thermal degradation and aqueous solution behavior were investigated at various temperatures, at concentrations above their corresponding critical aggregation concentration the copolymers readily self-assemble into large multicore structures composed of PCL domains and corona consisting of HBPG/SiHBPG branches.
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Evaluation of ‘surgery-friendly’ bone scaffold characteristics: 3D printed ductile BG/PCL scaffold with high inorganic content to repair critical bone defects
15 Dec 2022
TL;DR: Wang et al. as discussed by the authors used the solvent method to add high concentration (wt% 70%) bioglass (BG) into polycaprolactone (PCL), and polyethylene glycol was used as plasticizer to prepare 70% BG/PCL composite scaffolds with high ductility using 3D printing technology.
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Preparation, Characterization and Processing of PCL/PHO Blends by 3D Bioplotting
TL;DR: Blends of polycaprolactone (PCL) and poly(3-hydroxy octanoate) P(3HO) were prepared by melt compounding as discussed by the authors.
4
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