Journal Article10.1080/09205063.2017.1394711
PCL and PCL-based materials in biomedical applications
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TL;DR: PCL is a polyester that has been widely used in tissue engineering field for its availability, relatively inexpensive price and suitability for modification, and it can be used under harsh mechanical, physical and chemical conditions without significant loss of its properties.
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Abstract: Biodegradable polymers have met with an increasing demand in medical usage over the last decades. One of such polymers is poly(e-caprolactone) (PCL), which is a polyester that has been widely used in tissue engineering field for its availability, relatively inexpensive price and suitability for modification. Its chemical and biological properties, physicochemical state, degradability and mechanical strength can be adjusted, and therefore, it can be used under harsh mechanical, physical and chemical conditions without significant loss of its properties. Degradation time of PCL is quite long, thus it is used mainly in the replacement of hard tissues in the body where healing also takes an extended period of time. It is also used at load-bearing tissues of the body by enhancing its stiffness. However, due to its tailorability, use of PCL is not restricted to one type of tissue and it can be extended to engineering of soft tissues by decreasing its molecular weight and degradation time. This review ou...
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Citations
A 3D printed PCL/hydrogel construct with zone-specific biochemical composition mimicking that of the meniscus
TL;DR: An artificial meniscus is constructed mimicking the biochemical organization of the native tissue by 3D printing a meniscUS shaped PCL scaffold and then impregnating it with agarose (Ag) and gelatin methacrylate (GelMA) hydrogels in the inner and outer regions, respectively, which has a potential for use as a substitute for totalMeniscus replacement.
100
3D printed hydrogel/PCL core/shell fiber scaffolds with NIR-triggered drug release for cancer therapy and wound healing
TL;DR: In this paper, a core/shell fiber scaffold was fabricated by coating a homogeneous layer of polycaprolactone (PCL) on the 3D printed alginate-gelatin hydrogel scaffolds.
98
Additive Manufacturing Approaches for Hydroxyapatite-Reinforced Composites
Mario Milazzo,Mario Milazzo,Nicola Contessi Negrini,Nicola Contessi Negrini,Stefania Scialla,Benedetto Marelli,Silvia Farè,Serena Danti,Serena Danti,Serena Danti,Markus J. Buehler +10 more
TL;DR: In this paper, a review of additive manufacturing techniques to process hydroxapatite-reinforced composites and biocomposites for the production of scaffolds with biological matrices, including cellular tissues, is presented.
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Cerium oxide nanoparticles loaded nanofibrous membranes promote bone regeneration for periodontal tissue engineering.
Amaëlle Landais,Shuangshuang Ren,Chris Hamnett,Yi Zhou,Kai Zheng,David James,Xuanwen Xu,Jie Yang,Xiaoyu Wang,Leiying Miao,Hui Wei,Yan Xu +11 more
TL;DR: Electrospinning to fabricate fibrous membranes containing CeO2 NPs showed that the composite membranes improved mechanical properties as well as realized release of CeO3 NPs, and CeO1 NPs contained electrospun membrane may be a promising candidate material for periodontal bone regeneration.
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Microscopic Techniques for the Analysis of Micro and Nanostructures of Biopolymers and Their Derivatives.
Abhilash Venkateshaiah,Vinod V.T. Padil,Malladi Nagalakshmaiah,Stanisław Wacławek,Miroslav Černík,Rajender S. Varma +5 more
TL;DR: This review highlights the significance of various microscopic techniques incorporating the literature details that help characterize biopolymers and their derivatives.
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