Journal Article10.1039/C9NR00455F
Patterned plasmonic gradient for high-precision biosensing using a smartphone reader
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TL;DR: A metasurface-inspired bio-sensor, patterned plasmonic gradient (PPG), which transduces local index information into 2D patterns and provides a high performance bio-Sensing solution for the places where professional equipment is inaccessible.
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Abstract: Smartphone-compatible biosensors are believed to be one of the key techniques for improving the quality of diagnosis in remote areas. However, to date, few smartphone-compatible biosensors can reach the specifications of their conventional counterparts due to the limitations of consumer-grade detectors carried by phones. To circumvent this issue, we reported a metasurface-inspired bio-sensor, patterned plasmonic gradient (PPG), which transduces local index information into 2D patterns. By harnessing the powerful imaging and computational capability of modern smartphones, the PPG is sensitive enough to detect tiny refractive index changes induced by a submonolayer of molecules with high precision (Δn < 0.001) in a large dynamic range. It allows us to monitor the conjugation process between biotin and a trace amount of streptavidin (15 nM, 20 μL) in real-time. With high sensitivity and accuracy, the PPG provides a high performance bio-sensing solution for the places where professional equipment is inaccessible.
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TL;DR: In this article , a review of the recent progress of metamaterials and metasurfaces in molecular optical sensors is presented, along with the principles that govern plasmonic and dielectric metamurfaces along with their features, supported by numerous examples.
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Principles of odor coding in vertebrates and artificial chemosensory systems.
TL;DR: The biological olfactory system is the sensory system responsible for the detection of the chemical composition of the environment as mentioned in this paper, and it can be seen as the interface between the external world and the environment where receptor neurons or artificial chemosensors reside.
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Plasmonic nanosensors for point-of-care biomarker detection
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Principles of odor coding in vertebrates and artificial chemosensory systems
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TL;DR: The biological olfactory system is the sensory system responsible for the detection of the chemical composition of the environment as mentioned in this paper , and it can be seen as the interface between the external world and the environment where receptor neurons or artificial chemosensors reside.
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References
Light Propagation with Phase Discontinuities: Generalized Laws of Reflection and Refraction
Nanfang Yu,Patrice Genevet,Patrice Genevet,Mikhail A. Kats,Francesco Aieta,Francesco Aieta,Jean-Philippe Tetienne,Jean-Philippe Tetienne,Federico Capasso,Zeno Gaburro,Zeno Gaburro +10 more
TL;DR: In this article, a two-dimensional array of optical resonators with spatially varying phase response and subwavelength separation can imprint phase discontinuities on propagating light as it traverses the interface between two media.
8.8K
Extraordinary optical transmission through sub-wavelength hole arrays
Thomas W. Ebbesen,Thomas W. Ebbesen,Henri J. Lezec,H. F. Ghaemi,Tineke Thio,Peter A. Wolff,Peter A. Wolff +6 more
TL;DR: In this article, the optical properties of submicrometre cylindrical cavities in metallic films were explored and it was shown that arrays of such holes display highly unusual zero-order transmission spectra at wavelengths larger than the array period, beyond which no diffraction occurs.
8.2K
Biosensing with plasmonic nanosensors
TL;DR: This paper introduces the localized surface plasmon resonance (LSPR) sensor and describes how its exquisite sensitivity to size, shape and environment can be harnessed to detect molecular binding events and changes in molecular conformation.
7K
Flat Optics With Designer Metasurfaces
Nanfang Yu,Federico Capasso +1 more
TL;DR: This Review focuses on recent developments on flat, ultrathin optical components dubbed 'metasurfaces' that produce abrupt changes over the scale of the free-space wavelength in the phase, amplitude and/or polarization of a light beam.
5.6K
Light Propagation with Phase Discontinuities: Generalized Laws of Reflection and Refraction
Abstract: Light propagation can be controlled with plasmonic interfaces that introduce abrupt phase shifts along the optical path. Conventional optical components rely on gradual phase shifts accumulated during light propagation to shape light beams. New degrees of freedom are attained by introducing abrupt phase changes over the scale of the wavelength. A two-dimensional array of optical resonators with spatially varying phase response and subwavelength separation can imprint such phase discontinuities on propagating light as it traverses the interface between two media. Anomalous reflection and refraction phenomena are observed in this regime in optically thin arrays of metallic antennas on silicon with a linear phase variation along the interface, which are in excellent agreement with generalized laws derived from Fermat’s principle. Phase discontinuities provide great flexibility in the design of light beams, as illustrated by the generation of optical vortices through use of planar designer metallic interfaces.
5.1K