PARP-2, A Novel Mammalian DNA Damage-dependent Poly(ADP-ribose) Polymerase

TL;DR: The Y chromosome and several important genes on the Y chromosome that play critical roles in spermatogenesis in humans, and the three critical genes identified in the laboratory in autosomes involved in human sperMatogenesis, the SYCP3, MEI1 and PARP-2 are demonstrated.

TL;DR: The first such disease associated with hereditary mutations in PARP1 was reported in this article , where the affected individual possesses biallelic mutations in the second DNA strand-break sensing zinc finger of PARP, resulting in a predicted truncated protein of 127 amino acids.

TL;DR: This chapter discusses the development of and use of EMMARM, as well as some of the techniques used to develop E-modulus balloons, and their applications in the sport and literature.

TL;DR: A new criterion for triggering the extension of word hits, combined with a new heuristic for generating gapped alignments, yields a gapped BLAST program that runs at approximately three times the speed of the original.

TL;DR: A technique for conveniently radiolabeling DNA restriction endonuclease fragments to high specific activity is described, and these "oligolabeled" DNA fragments serve as efficient probes in filter hybridization experiments.

TL;DR: In this article, a technique for conveniently radiolabeling DNA restriction endonuclease fragments to high specific activity is described, where DNA fragments are purified from agarose gels directly by ethanol precipitation and are then denatured and labeled with the large fragment of DNA polymerase I, using random oligonucleotides as primers.

TL;DR: 5'-Noncoding sequences have been compiled from 699 vertebrate mRNAs and GCCA/GCCATGG emerges as the consensus sequence for initiation of translation in vertebrates.