Parallel evolution of cannabinoid biosynthesis

TL;DR: A comprehensive understanding of the underlying mechanism of cannabinoid biosynthesis is necessary to cultivate and promote globally the medicinal application of Cannabis resources and provide valuable insights into the efficient biosynthesis and green production of cannabinoids.

TL;DR: This study is an icebreaker for the dissection of phthalide biosynthetic pathway and reveals the hybrid origin of L. chuanxiong, which will facilitate the metabolic engineering for (S)-3-n-butylphthalide production and breeding for L. chuanxiong.

TL;DR: Sesquiterpene lactones are plant specialized metabolites with diverse biosynthetic, regulatory and signalling roles. They are derived from farnesyl pyrophosphate and are found in many plant families, especially Asteraceae. Recent findings have dramatically changed our knowledge about their biosynthesis and regulation.

TL;DR: The hypothesis that cannabinoids function in defense against chewing herbivores is supported, with results supporting the prediction that genotypes with greater concentrations of cannabinoids will have reduced herbivory.

TL;DR: This extends OrthoFinder’s high accuracy orthogroup inference to provide phylogenetic inference of orthologs, rooted genes trees, gene duplication events, the rooted species tree, and comparative genomic statistics.

TL;DR: Hifiasm as discussed by the authors is a de novo assembler that takes advantage of long high-fidelity sequence reads to faithfully represent the haplotype information in a phased assembly graph.

TL;DR: A comprehensive pipeline called Extensive de-novo TE Annotator (EDTA) is created that produces a filtered non-redundant TE library for annotation of structurally intact and fragmented elements and will greatly facilitate TE annotation in eukaryotic genomes.

TL;DR: The Assemblathon 2 as discussed by the authors presented a variety of sequence data to be assembled for three vertebrate species (a bird, a fish, and a snake) from 21 participating teams.