1. What are the contributions in "Ovarian cancer and oral contraceptives: collaborative reanalysis of data from 45 epidemiological studies" ?
For example, this paper found that the longer women had used oral contraceptives, the greater the reduction in ovarian cancer risk ( p < 0·0001 ).
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2. What are the future works mentioned in the paper "Ovarian cancer and oral contraceptives: collaborative reanalysis of data from 45 epidemiological studies" ?
The number of cancers prevented each year is likely to increase substantially in the future, with the further ageing of past users of oral contraceptives and the increasing numbers of new users, especially in middle-income and low-income countries.
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3. How long did oral contraceptives reduce ovarian cancer risk?
In high-income countries, 10 years use of oral contraceptives was estimated to reduce ovarian cancer incidence before age 75 from 1·2 to 0·8 per 100 users and mortality from 0·7 to 0·5 per 100; for every 5000 woman-years of use, about two ovarian cancers and one death from the disease before age 75 are prevented.
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4. How long does oral contraceptive use last?
Oral contraceptives can reduce the risk of ovarian cancer, but the eventual public-health eff ects of this reduction will depend on how long the protection lasts after use ceases.
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