Optimizing microarray in experimental hypertension
Frances Shannon,Katja U.S. McKenzie,Katja U.S. McKenzie,Amanda J. Edgley,Amanda J. Edgley,Sudha Rao,Sudha Rao,Kaiman Peng,Kaiman Peng,Amany Shweta,Amany Shweta,Chris G Schyvens,Chris G Schyvens,Warwick P Anderson,Warwick P Anderson,Sue Wilson,Sue Wilson,Yvonne Pittelkow,Yvonne Pittelkow,Stephen J. Ohms,Stephen J. Ohms,Judith A. Whitworth,Judith A. Whitworth +22 more
TL;DR: Despite the outbred nature of the rats used in this study, they are useful for gene expression profiling comparisons, andGene expression profiles in the left control kidney were extremely consistent across animals.
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About: This article is published in Kidney International. The article was published on 01 Jan 2005. and is currently open access. The article focuses on the topics: Gene expression profiling & Gene chip analysis.
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Citations
Mining Gene Expression Profile with Missing Values: An Integration of Kernel PCA and Robust Singular Values Decomposition
Md. Saimul Islam,Md. Aminul Hoque,Md. Sahidul Islam,Mohammad Ali,Md. Bipul Hossen,Md. Binyamin,Amir Feisal Merican,Kohei Akazawa,Nishith Kumar,Masahiro Sugimoto +9 more
TL;DR: This study concluded that KNN performed satisfactorily in generating a GE biplot in the presence of missing values in microarray data, and was smaller when the data matrix was imputed by KNN than by CM.
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TL;DR: A balanced probability analysis is presented, which provides the biologist with an approach to interpret results in the context of the total number of genes truly differentially expressed and false discovery and false negative rates for the list of genes reaching any significance threshold.
Differential gene expression profiling of large and small retinal ganglion cells
TL;DR: The results show that FACS-aided purification of retrogradely labeled cells can be effectively utilized for transcriptional profiling of adult retinal neurons.
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