Optic nerve head anatomy in myopia and glaucoma, including parapapillary zones alpha, beta, gamma and delta: Histology and clinical features
140
TL;DR: The optic nerve head can morphologically be differentiated into the optic disc with the lamina cribrosa as its basis, and the parapapillary region with zones alpha (irregular pigmentation due to irregularities of the retinal pigment epithelium and peripheral location), beta zone (complete RPE loss while Bruch's membrane (BM) is present), gamma zone (absence of BM), and delta zone (elongated and thinned peripapillary scleral flange).
read more
About: This article is published in Progress in Retinal and Eye Research. The article was published on 01 Jul 2021. and is currently open access. The article focuses on the topics: Optic disc & Optic nerve.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Myopic Versus Glaucomatous Parapapillary Beta Zone in Myopic Eyes Versus Eyes With Secondary Angle-Closure Glaucoma
TL;DR: In this article , the authors search for histologic differences in the beta zone between myopic eyes versus eyes with secondary angle-closure glaucoma, and find that the differences suggest different etiologies of the Glaucomatous versus myopic beta zone.
7
Prevalence and Associations of Non-Glaucomatous Optic Nerve Atrophy in High Myopia. The Ural Eye and Medical Study.
Mukharram M. Bikbov,E. M. Iakupova,Timur R. Gilmanshin,Guzel Bikbova,Gyulli M. Kazakbaeva,Songhomitra Panda-Jonas,L. I. Gilemzianova,Jost B. Jonas +7 more
TL;DR: In this ethnically mixed population from Russia with an age of 40+ years, high axial myopia showed a relatively high prevalence of NGOA, increasing with longer axial length and wider temporal parapapillary gamma zone, and may be a reason for visual field and central visual acuity loss, unexplainable by myopic macular pathologies.
7
Histology of neovascular myopic macular degeneration.
TL;DR: In this paper, the histological correlate of neovascular or exudative myopic macular degeneration (nMMD) in highly myopic human eyes was examined histomorphometrically histologic sections of enucleated eyes of Caucasian patients.
7
High Myopia Normative Database of Peripapillary Retinal Nerve Fiber Layer Thickness to Detect Myopic Glaucoma in Chinese Population.
Yunhe Song,Fei Li,Rachel S Chong,Wei Wang,Anran Ran,Feng Bin Lin,Peiyuan Wang,Zhenyu Wang,Jingwen Jiang,Kangjie Kong,Lingfei Jin,Meiling Chen,Jian Sun,Deming Wang,Clement C Y Tham,Dennis S.C. Lam,Linda M. Zangwill,Robert N. Weinreb,Tin Aung,Jost B. Jonas,Kyoko Ohno-Matsui,Ching-Yu Cheng,Neil M. Bressler,Xiaodong Sun,Carol Y. Cheung,Shida Chen,Xiu-zhi Zhang +26 more
TL;DR: The HM-specific normative database is more capable of detecting HMG eyes than the SS-OCT built-in database and may be an effective tool for differential diagnosis between HMG and HM.
7
Prevalence and Cause of Loss of Visual Acuity and Visual Field in Highly Myopic Eyes. The Beijing Eye Study.
TL;DR: Prevalence of MMD and optic neuropathy prevalence correlated with higher myopic refractive error and older age, and primary causes for MSVI and blindness were myopic macular degeneration, and branch macular retinal vein occlusion.
6
References
Optical Coherence Tomography
TL;DR: The optical coherence tomograph is a new, noninvasive technical device that can obtain cross-sectional, high-resolution images-optical coherencetomographs (OCT)-of the retina that permits an accurate evaluation of various macular and chorioretinal pathologies and the early detection of glaucomatous damage.
6.4K
Global Causes of Blindness and Distance Vision Impairment 1990-2020: A Systematic Review and Meta-Analysis
Seth Flaxman,Rupert R A Bourne,Serge Resnikoff,Serge Resnikoff,Peter Ackland,Tasanee Braithwaite,Maria V Cicinelli,Aditi Das,Jost B. Jonas,Jill E Keeffe,John H. Kempen,Janet L Leasher,Hans Limburg,Kovin Naidoo,Kovin Naidoo,Konrad Pesudovs,Alexander J Silvester,Gretchen A Stevens,Nina Tahhan,Nina Tahhan,Tien Yin Wong,Hugh R. Taylor,Rupert R A Bourne,Aries Arditi,Yaniv Barkana,Banu Bozkurt,Alain M. Bron,Donald L. Budenz,Feng Cai,Robert J Casson,Usha Chakravarthy,Jaewan Choi,Maria Vittoria Cicinelli,Nathan Congdon,Reza Dana,Rakhi Dandona,Lalit Dandona,Iva Dekaris,Monte A. Del Monte,Jenny deva,Laura E. Dreer,Leon B. Ellwein,Marcela Frazier,Kevin D. Frick,David S. Friedman,João M. Furtado,H. Gao,Gus Gazzard,Ronnie George,Stephen Gichuhi,Victor H. Gonzalez,Billy R. Hammond,Mary Elizabeth Hartnett,Minguang He,James F. Hejtmancik,Flavio E. Hirai,John J Huang,April D. Ingram,Jonathan C. Javitt,Jost B. Jonas,Charlotte E. Joslin,John H Kempen,Moncef Khairallah,Rohit C Khanna,Judy E. Kim,George N. Lambrou,Van C. Lansingh,Paolo Lanzetta,Jennifer I. Lim,Kaweh Mansouri,Anu A. Mathew,Alan R. Morse,Beatriz Munoz,David C. Musch,Vinay Nangia,Maria Palaiou,Maurizio Battaglia Parodi,Fernando Yaacov Pena,Tunde Peto,Harry A. Quigley,Murugesan Raju,Pradeep Y. Ramulu,Zane Rankin,Dana Reza,Alan L. Robin,Luca Rossetti,Jinan B. Saaddine,Mya Sandar,Janet B. Serle,Tueng T. Shen,Rajesh K. Shetty,Pamela C. Sieving,Juan Carlos Silva,Rita S. Sitorus,Dwight Stambolian,Gretchen Stevens,Hugh Taylor,Jaime Tejedor,James M. Tielsch,Miltiadis K. Tsilimbaris,Jan C. van Meurs,Rohit Varma,Gianni Virgili,Ya Xing Wang,Ningli Wang,Sheila K. West,Peter Wiedemann,Tien Wong,Richard Wormald,Yingfeng Zheng +109 more
TL;DR: A series of regression models were fitted to estimate the proportion of moderate or severe vision impairment and blindness by cause, age, region, and year, and found that world regions varied markedly in the causes of blindness and vision impairment in this age group.
2.8K
Enhanced depth imaging spectral-domain optical coherence tomography.
TL;DR: In this paper, a method to obtain images of the choroid using conventional spectral-domain optical coherence tomography (OCT) and to evaluate choroidal thickness measurements using these images was described.
2.1K
Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial.
TL;DR: Patients treated in the EMGT had half of the progression risk of control patients, including the effect of EMGT treatment, and the magnitude of initial IOP reduction was a major factor influencing outcome.
1.9K
Predictors of long-term progression in the early manifest glaucoma trial.
TL;DR: Treatment and follow-up IOP continued to have a marked influence on progression, regardless of baseline IOP, and lower systolic perfusion pressure, lower syStolic BP, and cardiovascular disease history emerged as new predictors, suggesting a vascular role in glaucoma progression.
1.3K