Open Access
Opioid analgesics and antagonists
T Reisine
- 01 Jan 1996
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About: The article was published on 01 Jan 1996. and is currently open access.
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Citations
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Dose ratio is important in maximizing naloxone enhancement of nalbuphine analgesia in humans.
Robert W. Gear,Newton C. Gordon,Christine Miaskowski,Steven M. Paul,Philip H. Heller,Jon D. Levine +5 more
TL;DR: The hypothesis that an important determinant of nAloxone enhancement of nalbuphine analgesia is the dose ratio of n albuphines to naloxone is tested is tested, suggesting that the anti-analgesic effect of nnalbu phine is present in both sexes at the 2.5 mg dose and that this is an importanteterminant of the analgesic efficacy of this combination.
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Production of antinociception by peripheral administration of [Lys7]dermorphin, a naturally occurring peptide with high affinity for μ-opioid receptors
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Differential mechanism of G-protein activation induced by endogenous mu-opioid peptides, endomorphin and beta-endorphin.
TL;DR: The subject of the present review is to focus on the differential mechanism underlying G-protein activation induced by these mu-opioid peptides using the [35S]GTPgammaS binding assay.
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