On the involvement of prefrontal networks in cognitive ageing.

TL;DR: A qualitative meta-analytic review of all the functional magnetic resonance imaging ageing studies and positron emission tomography ageing studies of WM and episodic memory that report PFC activation indicated that in normal ageing distinct PFC regions exhibit different patterns of functional change, suggesting that age-related changes in PFC function are not homogeneous in nature.

TL;DR: Cortical thickness and volume collectively confirmed the vulnerability of the prefrontal cortex, whereas in other cortical regions, such as in the parietal cortex, thickness was the only measure sensitive to the pronounced age-related atrophy.

TL;DR: Older adults showed reduced activation during the cue and delay period but increased activation at the time of the probe, particularly on high-interference trials, consistent with the hypothesis that age-related impairments in goal maintenance abilities cause a compensatory shift in older adults from a proactive to a reactive cognitive control strategy.

TL;DR: This chapter discusses the theoretical and empirical literature that addresses aging and discourse comprehension and a series of five studies guided by a particular working memory viewpoint regarding the formation of inferences during discourse processing are described.

TL;DR: The human frontal cortex helps mediate working memory, a system that is used for temporary storage and manipulation of information and that is involved in many higher cognitive functions.

TL;DR: Research on the risks associated with usual aging and strategies to modify them should help elucidate how a transition from usual to successful aging can be facilitated.

TL;DR: The destruction of transmodal epicentres causes global impairments such as multimodal anomia, neglect and amnesia, whereas their selective disconnection from relevant unimodal areas elicits modality-specific impairmentssuch as prosopagnosia, pure word blindness and category-specific anomias.