Journal Article10.1016/J.BBR.2012.03.022
Object recognition testing: Methodological considerations on exploration and discrimination measures
Sven Akkerman,Arjan Blokland,Olga A.H. Reneerkens,Nick P. van Goethem,Eva Bollen,Hieronymus J.M. Gijselaers,Cindy K.J. Lieben,Harry W.M. Steinbusch,Jos Prickaerts +8 more
202
TL;DR: Pre-experimental exposure (familiarization) to objects, habituation to treatment procedures, and the use of relative discrimination measures when using the ORT are suggested to take into consideration.
read more
About: This article is published in Behavioural Brain Research. The article was published on 01 Jul 2012. The article focuses on the topics: Object (computer science) & Discrimination learning.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Novel Object Recognition Test for the Investigation of Learning and Memory in Mice.
TL;DR: The object recognition test is a relatively low-stress, efficient test for memory in mice, and is appropriate for the detection of neuropsychological changes following pharmacological, biological, or genetic manipulations.
753
Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D.
Annerieke S.R. Sierksma,D.L.A. van den Hove,F. Pfau,M. Philippens,Olga Bruno,Ernesto Fedele,Roberta Ricciarelli,Harry W.M. Steinbusch,Tim Vanmierlo,Jos Prickaerts +9 more
TL;DR: GEBR-7b can enhance spatial memory function in the APPswe/PS1dE9 mouse model of AD and appears an interesting novel therapeutic option for cognitive deficits in AD.
127
The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties.
TL;DR: The systematic analysis suggests that a specific circuit between the medial prefrontal cortex, lateral EC and hippocampus encodes the information for event, place and time of occurrence into the complex episodic-like memory, as a top-down regulation from the mPFC onto the hippocampus.
116
Improved long-term memory via enhancing cGMP-PKG signaling requires cAMP-PKA signaling.
Eva Bollen,Daniela Puzzo,Kris Rutten,Lucia Privitera,Jochen De Vry,Tim Vanmierlo,Gunter Kenis,Agostino Palmeri,Rudi D'Hooge,Detlef Balschun,Harry Steinbusch,Arjan Blokland,Jos Prickaerts +12 more
TL;DR: It is demonstrated that cGMP/protein kinase G (PKG) signaling mediates early memory consolidation as well as early-phase LTP, whereas cAMP/ protein kinase A (PKA) signaling mediation mediates late consolidation and late-phase-like LTP.
114
Object recognition testing: Rodent species, strains, housing conditions, and estrous cycle
Nick P. van Goethem,Kris Rutten,Franz Josef van der Staay,Franz Josef van der Staay,L.A.W. Jans,Sven Akkerman,Harry W.M. Steinbusch,Arjan Blokland,José van’t Klooster,Jos Prickaerts +9 more
TL;DR: Object recognition appears to be a common ability of rodent species, but different strains have different memory capacities and sensitivities to scopolamine, individual housing leads to higher performance, and performance of females is dependent on the estrous cycle phase.
114
References
•Book
Statistical Power Analysis for the Behavioral Sciences
Jacob Cohen
- 01 Dec 1969
TL;DR: The concepts of power analysis are discussed in this paper, where Chi-square Tests for Goodness of Fit and Contingency Tables, t-Test for Means, and Sign Test are used.
124.4K
A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data.
TL;DR: A new memory test in rats, based on the differential exploration of familiar and new objects, which is comparable to memory tests currently used in man and allows interspecies comparisons.
3.3K
A new one-trial test for neurobiological studies of memory in rats. III. Spatial vs. non-spatial working memory
TL;DR: There is no correlation between the three tests which argues for a multiple form of working memory, especially a spatial and a non-spatial one, and the level of discrimination in the spatial recognition test was significantly reduced compared to that of control.
1.2K
Object recognition in rats and mice: a one-trial non-matching-to-sample learning task to study 'recognition memory'
Rick A. Bevins,Joyce Besheer +1 more
TL;DR: The object-recognition task has been used to study mutant mice, aging deficits, early developmental influences, nootropic manipulations, teratological drug exposure and novelty seeking.
1.2K