Obesity and glycemic control among people with type 2 diabetes in the United States: A retrospective cohort study using insurance claims data.
Kristina S. Boye,Maureen J. Lage,Vivian T. Thieu,Shraddha Shinde,Shivanie Dhamija,Jay Patrick Bae +5 more
25
TL;DR: In this paper, the authors examined the relationship between body mass index (BMI) and HbA1c for individuals with Type 2 diabetes (T2D) in the United States, using data from IBM® MarketScan® Explorys® Claims-EMR Data for the years 2012-2019.
read more
Abstract: Aims To examine body mass index (BMI) and HbA1c for individuals with type 2 diabetes (T2D) in the United States. Methods The retrospective study utilized data from IBM® MarketScan® Explorys® Claims-EMR Data for the years 2012–2019. Individuals with T2D and a recorded HbA1c laboratory result and BMI were included. The relationship between BMI and HbA1c was assessed descriptively and logistic regressions examined the relationship between benchmark BMI and the probability of having HbA1c above targets of 7% or 8% in the 1 year post-period. Results In our sample of 44,723 patients, results indicated that compared to individuals of normal weight, those classified as obese class I or obese class II were 24% more likely to have a last HbA1c ≥ 7% (Odds Ratio [OR] = 1.24; 95% Confidence Interval [CI] 1.14–1.35 for both obese class I and obese class II), while those classified as obese class III were 16% more likely (OR = 1.16; 95% CI 1.06–1.27). Results were similar when using a HbA1c threshold of 8%. Conclusions Given the importance of glycemic control for people with T2D, these results suggest that treatments which reduce rates of obesity may help to improve health outcomes.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Long‐term cost‐effectiveness analysis of tirzepatide versus semaglutide 1.0 mg for the management of type 2 diabetes in the United States
TL;DR: In this paper , the authors evaluated the long-term cost-effectiveness of tirzepatide (5, 10 and 15 mg), a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP•1) receptor agonist, versus semaglutide 1.0 mg, an injectable glucagon•like peptides-1 receptor agonists, from a US healthcare payer perspective.
9
Factors associated with treatment adherence to treatment among in patients with type 2 diabetes in Iran: A cross-sectional study
Nasrin Pourhabibi,Bahram Mohebbi,Roya Sadeghi,Elham Shakibazadeh,Mojgan Sanjari,Azar Tol,Mehdi Yaseri +6 more
TL;DR: In this article , the authors conducted a cross-sectional study on 704 patients with type 2 diabetes referred to three diabetes clinics in Kerman, Iran and found that health literacy, HbA1c, and income were the main predictors of diabetes treatment adherence.
Prevalence of Obesity and Cardiovascular Risk Factors Among Type 2 Diabetes Mellitus Patients in Al-Khobar, Saudi Arabia
TL;DR: In this article , the prevalence of obesity in patients with Type II diabetes mellitus at King Fahd University Hospital (KFUH), Al-Khobar, and to assess the relationship between T2DM and cardiovascular risk factors with body mass index (BMI) and waist to hip ratio (WHR).
The effects of the ketogenic diet for the management of type 2 diabetes mellitus: A systematic review and meta-analysis of recent studies
Kimberley Yu Ching Choy,Jimmy Chun Yu Louie +1 more
- 01 Nov 2023
TL;DR: The ketogenic diet may improve lipid profiles but showed no additional benefits for glycaemic control or weight loss compared to control diets in type 2 diabetes patients over two years.
7
Sex Differences in White Adipose Tissue Expansion: Emerging Molecular Mechanisms
Simon T. Bond,Anna C. Calkin,Brian G. Drew +2 more
TL;DR: This review explores sex differences in white adipose tissue expansion, highlighting emerging molecular mechanisms underlying sexual dimorphism in obesity, which cannot be solely explained by hormones, and are influenced by coordinated gene networks and regulators.
5
References
•Journal Article
Prevalence of Obesity and Severe Obesity Among Adults: United States, 2017-2018.
TL;DR: This report provides the most recent national data for 2017-2018 on obesity and severe obesity prevalence among adults by sex, age, and race and Hispanic origin.
Benefits of Modest Weight Loss in Improving Cardiovascular Risk Factors in Overweight and Obese Individuals With Type 2 Diabetes
Rena R. Wing,Wei Lang,Thomas A. Wadden,Monika M. Safford,William C. Knowler,Alain G. Bertoni,James O. Hill,Frederick L. Brancati,Anne L. Peters,Lynne E. Wagenknecht +9 more
TL;DR: Modest weight losses of 5 to <10% were associated with significant improvements in CVD risk factors at 1 year, but larger weight losses had greater benefits.
1.7K
Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial.
Rena R. Wing,Judy Bahnson,George A. Bray,Jeanne M. Clark,Mace Coday,Caitlin Egan,Mark A. Espeland,John P. Foreyt,Edward W. Gregg,Valerie Goldman,Steven M. Haffner,Helen P. Hazuda,James O. Hill,Edward S. Horton,Van S. Hubbard,John M. Jakicic,Robert W. Jeffery,Karen C. Johnson,Steven E. Kahn,Tina Killean,Abbas E. Kitabchi,Cora E. Lewis,Cathy Manus,Barbara J. Maschak-Carey,Sara Michaels,Maria G. Montez,Brenda Montgomery,David M. Nathan,Jennifer Patricio,Anne L. Peters,Xavier Pi-Sunyer,Henry J. Pownall,David M. Reboussin,W. Jack Rejeski,Richard R. Rubin,Monika M. Safford,Tricia Skarphol,Brent Van Dorsten,Thomas A. Wadden,Lynne E. Wagenknecht,Jacqueline Wesche-Thobaben,Delia S. West,Donald A. Williamson,Susan Z. Yanovski +43 more
TL;DR: Intensive lifestyle intervention can produce sustained weight loss and improvements in fitness, glycemic control, and CVD risk factors in individuals with type 2 diabetes.
What causes the insulin resistance underlying obesity
TL;DR: The need to better understand the mechanisms linking visceral adiposity with liver fat accumulation, the mechanisms by which ectopic fat accumulation cause insulin resistance, and the size of adipose tissue depots is determined is underscored.
518
A Randomized Study on the Effect of Weight Loss on Obstructive Sleep Apnea Among Obese Patients With Type 2 Diabetes: The Sleep AHEAD Study
Gary D. Foster,Kelley E. Borradaile,Mark H. Sanders,Richard P. Millman,Gary Zammit,Anne B. Newman,Thomas A. Wadden,David R. Kelley,Rena R. Wing,F. Xavier Pi-Sunyer,David M. Reboussin,Samuel T. Kuna +11 more
TL;DR: In this paper, the effect of weight loss, produced through an intensive lifestyle intervention, on obstructive sleep apnea in obese patients with type 2 diabetes, was investigated using a randomized controlled trial design over a 1-year period.
513