Journal Article10.1176/APPI.AJP.158.5.735
Neuropsychological dysfunction in depressed suicide attempters.
John G. Keilp,Harold A. Sackeim,Beth S. Brodsky,Maria A. Oquendo,Kevin M. Malone,J. John Mann +5 more
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TL;DR: Neuropsychological deficits in depressed patients with high-lethality prior suicide attempts suggest impairment of executive functioning beyond that typically found in major depression.
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Abstract: OBJECTIVE: Neuropsychological deficits in the context of psychiatric disease may be associated with suicide risk. In this study, neuropsychological performance was compared among depressed patients with at least one prior suicide attempt of high lethality, depressed patients with low-lethality prior attempts, depressed patients with no prior suicide attempts, and nonpatients. METHOD: Fifty unmedicated patients in a major depressive episode (21 with no history of suicide attempts and 14 and 15 patients with previous attempts of low and high lethality, respectively) and 22 nonpatients were assessed. Groups were comparable in age, education, occupational level, and estimated premorbid intelligence. The neuropsychological battery produced scores within five composite domains: general intellectual functioning (current), motor functioning, attention, memory, and executive functioning. RESULTS: Patients whose prior suicide attempts were of high lethality performed significantly worse than all groups on tests of ...
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Citations
Systems Neuroscience in Late-Life Depression
Kevin J. Manning,David C. Steffens +1 more
- 01 Jan 2016
TL;DR: In this paper, three prominent functional networks in LLD have been identified: (1) a cognitive control network (CCN) active during cognitively demanding tasks, (2) a default mode network active during resting state and inhibited during cognitive demanding activity that is involved in internal mentation, and (3) a salience network relevant to attending to survival-relevant events in the environment.
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Difference in Cognitive Flexibility between Passive and Active Suicidal Ideation in Patients with Depression
Yi Jyunn Lai,Hsiang Chi Tan,Chin Ting Wang,Wan Chi Wu,Ling Yi Wang,Yu Chih Shen +5 more
- 01 Jan 2018
TL;DR: It is found that patients with active SI are associated with greater cognitive inflexibility than those with passive SI, which can provide insight into improved prevention.
Neurocognition and the Suicidal Process.
Sarah B Rutter,N Cipriani,E C Smith,Elizabeth Ramjas,D H Vaccaro,M Martin Lopez,William Calabrese,D Torres,P Campos-Abraham,M Llaguno,E Soto,Mona Ghavami,M. Mercedes Perez-Rodriguez +12 more
TL;DR: There seems to be a role both for cognitive distortions and neurocognitive deficits in the suicidal process, which warrant further exploration both separately and together.
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Attentional control deficits and suicidal ideation variability: An ecological momentary assessment study in major depression.
TL;DR: In this article , the authors examined attentional control capacities associated with SI variability and severity in ninety-five subjects with major depressive disorder, and quantified SI and depressive affect using Ecological Momentary Assessment (EMA) over a 7-day period.
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The Cycle of Schizoaffective Disorder, Cognitive Ability, Alcoholism, and Suicidality
TL;DR: The history of prominent mood syndromes characteristic of schizoaffective disorder contributes to increased risk of suicidal behaviors and cognitive dysfunction and/or alcoholism did not contribute additionally to risk.
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