Journal Article10.1176/APPI.AJP.158.5.735
Neuropsychological dysfunction in depressed suicide attempters.
John G. Keilp,Harold A. Sackeim,Beth S. Brodsky,Maria A. Oquendo,Kevin M. Malone,J. John Mann +5 more
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TL;DR: Neuropsychological deficits in depressed patients with high-lethality prior suicide attempts suggest impairment of executive functioning beyond that typically found in major depression.
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Abstract: OBJECTIVE: Neuropsychological deficits in the context of psychiatric disease may be associated with suicide risk. In this study, neuropsychological performance was compared among depressed patients with at least one prior suicide attempt of high lethality, depressed patients with low-lethality prior attempts, depressed patients with no prior suicide attempts, and nonpatients. METHOD: Fifty unmedicated patients in a major depressive episode (21 with no history of suicide attempts and 14 and 15 patients with previous attempts of low and high lethality, respectively) and 22 nonpatients were assessed. Groups were comparable in age, education, occupational level, and estimated premorbid intelligence. The neuropsychological battery produced scores within five composite domains: general intellectual functioning (current), motor functioning, attention, memory, and executive functioning. RESULTS: Patients whose prior suicide attempts were of high lethality performed significantly worse than all groups on tests of ...
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Citations
Neurocognitive performance predicts treatment outcome with cognitive behavioral therapy for major depressive disorder.
TL;DR: Results suggest that the structure of CBT may particularly benefit individuals with mild depression-related neurocognitive difficulties during a depressive episode and further research is needed to examine these patient characteristics and their potential contribution to the mechanisms ofCBT efficacy.
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A qualitative systematic review of neurocognition in suicide ideators and attempters: Implications for cognitive-based psychotherapeutic interventions.
Aleksandra Lalovic,Shijing Wang,Shijing Wang,John G. Keilp,Christopher R. Bowie,Sidney H. Kennedy,Sidney H. Kennedy,Sidney H. Kennedy,Sakina J. Rizvi,Sakina J. Rizvi,Sakina J. Rizvi +10 more
TL;DR: A systematic qualitative review of the published data on neurocognition in suicide ideators and attempters in order to clarify which neurocognitive targets may be most relevant to address using cognitive-based psychotherapeutic strategies in patients at risk for suicide as discussed by the authors.
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Coincident alcohol dependence and depression increases risk of suicidal ideation among Army National Guard soldiers
Gregory H. Cohen,Gregory H. Cohen,David S. Fink,Laura Sampson,Marijo Tamburrino,Israel Liberzon,Joseph R. Calabrese,Sandro Galea +7 more
TL;DR: It is found that alcohol dependence and depression interact statistically in shaping risk for incident suicidal ideation among Army National Guard service members and a high-risk prevention approach including population-based screening for suicidality among patients with alcohol dependence, depression, and particularly those with both conditions is warranted in military populations.
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Cognitive inhibition in suicidal depressed elderly: a case-control pilot study.
Stéphane Richard-Devantoy,Cédric Annweiler,Didier Le Gall,Jean-Bernard Garré,Jean-Pierre Olié,Olivier Beauchet +5 more
TL;DR: The aim of this case-control study was to compare cognitive inhibition performance in suicidal and nonsuicidal depressed older patients.
Understanding Suicide
Sharon A. Gutman
- 17 Mar 2005
TL;DR: The demography, risk factors, and biological underpinnings of suicidal behavior, particularly the mood disorders, personality disorders, anxiety disorders, and schizophrenia, are reviewed.
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