Journal Article10.1176/APPI.AJP.158.5.735
Neuropsychological dysfunction in depressed suicide attempters.
John G. Keilp,Harold A. Sackeim,Beth S. Brodsky,Maria A. Oquendo,Kevin M. Malone,J. John Mann +5 more
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TL;DR: Neuropsychological deficits in depressed patients with high-lethality prior suicide attempts suggest impairment of executive functioning beyond that typically found in major depression.
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Abstract: OBJECTIVE: Neuropsychological deficits in the context of psychiatric disease may be associated with suicide risk. In this study, neuropsychological performance was compared among depressed patients with at least one prior suicide attempt of high lethality, depressed patients with low-lethality prior attempts, depressed patients with no prior suicide attempts, and nonpatients. METHOD: Fifty unmedicated patients in a major depressive episode (21 with no history of suicide attempts and 14 and 15 patients with previous attempts of low and high lethality, respectively) and 22 nonpatients were assessed. Groups were comparable in age, education, occupational level, and estimated premorbid intelligence. The neuropsychological battery produced scores within five composite domains: general intellectual functioning (current), motor functioning, attention, memory, and executive functioning. RESULTS: Patients whose prior suicide attempts were of high lethality performed significantly worse than all groups on tests of ...
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Citations
Using resting-state intrinsic network connectivity to identify suicide risk in mood disorders.
Jonathan P. Stange,Lisanne M. Jenkins,Stephanie Pocius,Kayla A. Kreutzer,Katie L. Bessette,Sophie R. DelDonno,Leah R. Kling,Runa Bhaumik,Robert C. Welsh,John G. Keilp,K. Luan Phan,Scott A. Langenecker +11 more
TL;DR: The results suggest that individuals with a history of SB in the context of mood disorders may show reliably distinct patterns of intrinsic network connectivity, even when compared to those with mood disorders without SB.
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Do cerebrovascular risk factors confer risk for suicide in later life? A case-control study.
TL;DR: CVRF scores were significantly higher in suicide cases than community-dwelling comparison subjects after accounting for age, sex, depression diagnosis, and functional status, and Cerebrovascular disease may predispose to suicide in older adults by a variety of psychopathological means.
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Decision-making performance of depressed patients within 72 h following a suicide attempt.
TL;DR: Individuals with a recent suicide attempt showed decision-making dysfunction on both IGT versions of the Iowa Gambling Task, but on the EFGH, the overall difference between groups was not significant, depressed participants' performance remained poor during all blocks.
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Toxoplasma gondii, Suicidal Behavior, and Intermediate Phenotypes for Suicidal Behavior
Teodor T. Postolache,Abhishek Wadhawan,Dan Rujescu,Andrew J. Hoisington,Aline Dagdag,Enrique Baca-García,Christopher A. Lowry,Christopher A. Lowry,Christopher A. Lowry,Olaoluwa O. Okusaga,Olaoluwa O. Okusaga,Olaoluwa O. Okusaga,Lisa A. Brenner,Lisa A. Brenner +13 more
TL;DR: A detailed review of the associations between Toxoplasma gondii serology and suicidal behavior can be found in this paper, where the authors reported that an abundance of evidence supports a positive link between suicide attempts (but not suicidal ideation) and T.gondii immunoglobulin (IgG) positives.
Planning of suicide attempts among depressed inpatients ages 50 and over
Kenneth R. Conner,Paul R. Duberstein,Anthony Beckman,Marnin J. Heisel,Marnin J. Heisel,Jameson K. Hirsch,Stephanie A. Gamble,Yeates Conwell +7 more
TL;DR: Depressed patients with lower cognitive functioning and impairments in physical self-care may be especially vulnerable to impulsive suicidal behavior.
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References
“Mini-mental state”: A practical method for grading the cognitive state of patients for the clinician
Marshal F. Folstein,Marshal F. Folstein,Susan E B Folstein,Susan E B Folstein,Paul R. McHugh,Paul R. McHugh +5 more
TL;DR: A simplified, scored form of the cognitive mental status examination, the “Mini-Mental State” (MMS) which includes eleven questions, requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
86.6K
A practical method for grading the cognitive state of patients for the clinician
Marshal Folstein,Susan E B Folstein,F. Folstein,Paul R. McHugh +3 more
- 01 Jan 2002
TL;DR: The Mini-Mental State (MMS) as mentioned in this paper is a simplified version of the standard WAIS with eleven questions and requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
70.8K
Half a century of research on the Stroop effect: an integrative review.
TL;DR: It is concluded that recent theories placing the explanatory weight on parallel processing of the irrelevant and the relevant dimensions are likely to be more sucessful than are earlier theories attempting to locate a single bottleneck in attention.
The Structured Clinical Interview for DSM-III-R (SCID). I: History, rationale, and description.
TL;DR: The history, rationale, and development of the Structured Clinical Interview for DSM-III-R (SCID) is described, which is a semistructured interview for making the major Axis I DSM- III-R diagnoses.
4.5K
The neural correlates of the verbal component of working memory.
TL;DR: Comparisons of distribution of cerebral blood flow in these conditions localized the phonological store to the left supramarginal gyrus whereas the subvocal rehearsal system was associated with Broca's area, the first demonstration of the normal anatomy of the components of the 'articulatory loop'.
2.3K