Neuropeptide transmission in brain circuits
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TL;DR: In this article, the authors review converging data revealing a complex interaction between slow-acting neuromodulator peptides and fast-acting amino acid transmitters in the control of energy homeostasis, drug addiction, mood and motivation, sleep-wake states, and neuroendocrine regulation.
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About: This article is published in Neuron. The article was published on 04 Oct 2012. and is currently open access. The article focuses on the topics: Neuropeptide FF receptor & Neuropeptide Y receptor.
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References
Somatodendritic Secretion in Oxytocin Neurons Is Upregulated during the Female Reproductive Cycle
Christiaan P. J. de Kock,Keimpe D. Wierda,Laurens W. J. Bosman,Rogier Min,Jan-Jurjen Koksma,Huibert D. Mansvelder,Matthijs Verhage,Arjen B. Brussaard +7 more
TL;DR: It is demonstrated that somatodendritic release is augmented during lactation, which is a novel form of plasticity to change the strength of synaptic transmission.
Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system.
TL;DR: Hypocretin-1 and -2 depolarized hypocretin neurons and evoked an increase in spike frequency, which represents a possible mechanism for orchestrating the output of the diffuse hypothalamic arousal system.
Calbindin controls release probability in ventral tegmental area dopamine neurons
Ping-Yue Pan,Timothy A. Ryan +1 more
TL;DR: It is found that pHluorin-tagged vesicular monoamine transporter 2 in dopamine neurons is more loosely coupled to calcium entry than in fast synapses, which allows exocytosis to be efficiently controlled by a native fast calcium buffer, calbindin-D28k.
Evidence that the nucleotide exchange and hydrolysis cycle of G proteins causes acute desensitization of G-protein gated inward rectifier K+ channels
TL;DR: A positive regulatory function of R GS4 is uncovered in this study; the opposing effects allow RGS4 to potentiate acute desensitization without compromising GIRK activation.
The Fine Structure of the Nervous System.
TL;DR: This is the first atlas of the ultrastructure of the mature nervous system and it is a relatively complete collection of elegant micrographs with an accompanying text that explores the role that thin astrocytic processes may play in isolating receptive surfaces, thereby preventing axon terminals from influencing.
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