Journal Article10.1016/J.BIOMATERIALS.2005.06.035
Neurite bridging across micropatterned grooves.
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TL;DR: The ability of microfabricated biomaterials to support neurite extension across micropatterned grooves with feature sizes on the order of tens of microns, sizes relevant to the design of biomaterialS and tissue engineering scaffolds are reported.
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About: This article is published in Biomaterials. The article was published on 01 Jan 2006. The article focuses on the topics: Neurite.
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Citations
Engineering of adult human neural stem cells differentiation through surface micropatterning.
Amélie Béduer,Christophe Vieu,Christophe Vieu,Florent Arnauduc,Jean-Christophe Sol,Isabelle Loubinoux,Isabelle Loubinoux,Laurence Vaysse,Laurence Vaysse +8 more
TL;DR: The results demonstrate that precoated micropatterned PDMS surfaces can serve as effective neurite guidance surfaces for human neural stem cells and obtain neuron development and differentiation rate comparable to a plane unpatterned surface, with an efficient neurite advice and a long-term cell viability.
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Controlling the morphology and outgrowth of nerve and neuroglial cells: The effect of surface topography.
TL;DR: The present review paper aims at reviewing the existing body of literature on the use of artificial micro- and nano-topographical features to control neuronal and neuroglial cells' morphology, outgrowth and neural network topology.
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In Vitro Assessment of Axonal Growth Using Dorsal Root Ganglia Explants in a Novel Three-Dimensional Collagen Matrix
Ahmet Bozkurt,Gary A. Brook,Sven Moellers,F. Lassner,Bernd Sellhaus,Joachim Weis,Michael Woeltje,Julian Tank,Christina Beckmann,Paul Fuchs,Leon Olde Damink,Frank Schügner,Ingo Heschel,Norbert Pallua +13 more
TL;DR: The microstructural properties of the scaffold and in vitro data after DRG loading (axonal regeneration along migrated and columnar-aligned SCs resembling "Band of Büngner") suggest that this novel oriented 3D collagen scaffold serves as a basis for future experimental regeneration studies in the PNS.
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In vitro cell alignment obtained with a Schwann cell enriched microstructured nerve guide with longitudinal guidance channels.
Ahmet Bozkurt,Ronald Deumens,Ronald Deumens,Christina Beckmann,Leon Olde Damink,Frank Schügner,Ingo Heschel,Bernd Sellhaus,Joachim Weis,Wilhelm Jahnen-Dechent,Gary A. Brook,Norbert Pallua +11 more
TL;DR: It is concluded that orientated 3D nerve guides (decorated with SCs) with their physical and molecular properties may hold great promise in the repair of peripheral nerve lesion and serve as a basis for future experimental regeneration studies.
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The design of electrospun PLLA nanofiber scaffolds compatible with serum-free growth of primary motor and sensory neurons.
Joseph M. Corey,Caitlyn C. Gertz,Bor Shuen Wang,Lisa K. Birrell,Sara L. Johnson,David C. Martin,Eva L. Feldman +6 more
TL;DR: The development of poly(L-lactic acid) (PLLA) nanofiber substrates that support serum-free growth of primary motor and sensory neurons at low plating densities are reported.
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