Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
Abhishek K. Jha,Stanley Ching-Cheng Huang,Alexey Sergushichev,Alexey Sergushichev,Vicky Lampropoulou,Yulia Ivanova,Ekaterina Loginicheva,Karina Chmielewski,Kelly M. Stewart,Juliet Ashall,Bart Everts,Edward J. Pearce,Edward M. Driggers,Maxim N. Artyomov +13 more
TL;DR: An integrated high-throughput transcriptional-metabolic profiling and analysis pipeline provides a highly integrated picture of the physiological modules supporting macrophage polarization, identifying potential pharmacologic control points for both macrophages.
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About: This article is published in Immunity. The article was published on 17 Mar 2015. and is currently open access. The article focuses on the topics: Macrophage polarization.
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