Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.

TL;DR: The results show the highly dynamic nature of the macrophage response at the molecular level after an acute tissue injury and subsequent repair, and associate a specific signature of macrophages to predictive specialized functions ofmacrophages at each step of tissue injury/repair.

TL;DR: A number of factors, including oncostatin M, have been shown to promote osteoblast formation both in vitro and in vivo and how this can be used to direct new bone anabolic approaches is discussed.

TL;DR: In this article , the authors proposed a comprehensive diabetes care center focusing on panvascular diseases, which would leverage the advantages of a cross-disciplinary approach to achieve better integration of the pathogenesis and therapeutic evidence.

TL;DR: It is shown that BCAT1 is the predominant BCAT isoform in human primary macrophages and that oral administration of ERG240 reduces the severity of collagen-induced arthritis in mice and crescentic glomerulonephritis in rats by decreasing macrophage infiltration.

TL;DR: The third edition, coming ten years after the first, emphasizes both the flowering of biochemical research and the prodigious effort by busy teachers and scientists to keep up to date this popular text and reference.

TL;DR: The identification of mechanisms and molecules associated with macrophage plasticity and polarized activation provides a basis for Macrophage-centered diagnostic and therapeutic strategies.

TL;DR: KEGG Mapper, a collection of tools for KEGG PATHWAY, BRITE and MODULE mapping, enabling integration and interpretation of large-scale data sets and recent enhancements to the K EGG content, especially the incorporation of disease and drug information used in practice and in society, to support translational bioinformatics.

TL;DR: The four stages of orderly inflammation mediated by macrophages are discussed: recruitment to tissues; differentiation and activation in situ; conversion to suppressive cells; and restoration of tissue homeostasis.