Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.

TL;DR: In this article , a gas chromatography-mass spectrometry (GC-MS)-based metabolomics approach was employed to characterize the metabolic signatures and pathways underlying responses of Pacific white shrimp (Penaeus vannamei ) to hypoxia and to identify associated candidate biomarkers.

TL;DR: An increase in phospholipids that was accompanied by an up‐regulation of fatty acid synthase (FAS), a key enzyme in lipid synthesis is found, indicating metabolic reprogramming of THP‐1 cells by DNCB.

TL;DR: The metabolic network segmentation (MNS) algorithm is presented, a probabilistic graphical modeling approach that enables genome-scale, automated prediction of regulated metabolic reactions from differential or serial metabolomics data and contributes to the understanding of metabolic processes and their interplay with cellular signaling and regulation processes.

TL;DR: It is indicated that para-inflammation exhibited a protective effect in wound healing and provided new insight for host tissue repair.

TL;DR: The third edition, coming ten years after the first, emphasizes both the flowering of biochemical research and the prodigious effort by busy teachers and scientists to keep up to date this popular text and reference.

TL;DR: The identification of mechanisms and molecules associated with macrophage plasticity and polarized activation provides a basis for Macrophage-centered diagnostic and therapeutic strategies.

TL;DR: KEGG Mapper, a collection of tools for KEGG PATHWAY, BRITE and MODULE mapping, enabling integration and interpretation of large-scale data sets and recent enhancements to the K EGG content, especially the incorporation of disease and drug information used in practice and in society, to support translational bioinformatics.

TL;DR: The four stages of orderly inflammation mediated by macrophages are discussed: recruitment to tissues; differentiation and activation in situ; conversion to suppressive cells; and restoration of tissue homeostasis.