Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.

TL;DR: Polylactide degradation activates immune cells by metabolic reprogramming, leading to excessive inflammation and fibrosis. By targeting metabolic reprogramming, inflammatory responses can be reduced and anti-inflammatory signals stimulated.

TL;DR: In this article , the authors analyzed 317 urine proteomes, including 86 COVID-19, 55 pneumonia and 176 healthy controls, and identified specific RNA virus detector protein DDX58/RIG-I only in COVID19 samples.

TL;DR: In this paper , the functions of macrophages induced by simultaneous stimulation with lipopolysaccharide (LPS) and interleukin 4 (IL-4) were analyzed.

TL;DR: In this paper , the authors investigated whether exercise-enhanced production of proresolving lipid mediators contribute to alterations in macrophage intermediary metabolism, which may contribute to the anti-inflammatory effects of exercise.

TL;DR: The third edition, coming ten years after the first, emphasizes both the flowering of biochemical research and the prodigious effort by busy teachers and scientists to keep up to date this popular text and reference.

TL;DR: The identification of mechanisms and molecules associated with macrophage plasticity and polarized activation provides a basis for Macrophage-centered diagnostic and therapeutic strategies.

TL;DR: KEGG Mapper, a collection of tools for KEGG PATHWAY, BRITE and MODULE mapping, enabling integration and interpretation of large-scale data sets and recent enhancements to the K EGG content, especially the incorporation of disease and drug information used in practice and in society, to support translational bioinformatics.

TL;DR: The four stages of orderly inflammation mediated by macrophages are discussed: recruitment to tissues; differentiation and activation in situ; conversion to suppressive cells; and restoration of tissue homeostasis.