Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.

TL;DR: The divergent results obtained documented that the formation of lipoxidation adducts can have either anti-carcinogenic or pro-cARCinogenic effects, depending on the cell type affected and the specific adduct formed.

TL;DR: This study suggests that SLC37A2 dampens murine macrophages inflammation by down-regulating glycolytic reprogramming as a part of macrophage negative feedback system to curtail acute innate activation.

TL;DR: In this article, the authors discuss recent developments and emerging concepts in understanding of the impact amino acid availability and consumption has on cellular phenotype focusing on two key myeloid cell populations, macrophages and myELoid derived suppressor cells (MDSCs).

TL;DR: In this article, the role of distinct subsets of macrophages in the pathogenesis of multiple sclerosis and different therapeutic agents that target these cells are reviewed, and different strategies may require to target the various myeloid cell populations.

TL;DR: The third edition, coming ten years after the first, emphasizes both the flowering of biochemical research and the prodigious effort by busy teachers and scientists to keep up to date this popular text and reference.

TL;DR: The identification of mechanisms and molecules associated with macrophage plasticity and polarized activation provides a basis for Macrophage-centered diagnostic and therapeutic strategies.

TL;DR: KEGG Mapper, a collection of tools for KEGG PATHWAY, BRITE and MODULE mapping, enabling integration and interpretation of large-scale data sets and recent enhancements to the K EGG content, especially the incorporation of disease and drug information used in practice and in society, to support translational bioinformatics.

TL;DR: The four stages of orderly inflammation mediated by macrophages are discussed: recruitment to tissues; differentiation and activation in situ; conversion to suppressive cells; and restoration of tissue homeostasis.