Nasal obstruction as a key symptom in allergic rhinitis: efficacy and safety of a medical device in children.

TL;DR: The data show that the addition of dexpanthenol to an alpha-sympathomimetic nasal spray not only improves its tolerability but also further increases its effectiveness and leads to expedited cure.

TL;DR: Exploring the potential of lactoferrin in managing allergic airway diseases among children. Lactoferrin exhibits anti-inflammatory, antioxidant, antimicrobial, and immunomodulatory properties, making it a promising candidate for alleviating allergic diseases in children.

TL;DR: The most relevant nutraceuticals and non-pharmacological remedies used in managing patients with allergic rhinitis are reviewed and discussed in this article , where some compounds, such as micronutrients, vitamins, probiotics, herbal medicines, hyaluronic acid, and saline solutions, could positively and safely be used in children with AR as addon remedies.

TL;DR: The proposed formulation enables to combine the anti-inflammatory, antihistaminic, decongestant, anticholinergic, and hydrating effects of these drugs into a single medicine.

TL;DR: The rise in prevalence of symptoms in many centres is concerning, but the absence of increases in prevalence in asthma symptoms for centres with existing high prevalence in the older age-group is reassuring.

TL;DR: A new subdivision of allergic rhinitis is proposed and suggests evidence-based management of the disease using a stepwise approach and it is proposed that allergic patients are treated globally to combine treatment of upper and lower airway disease.

TL;DR: Current guidelines emphasize the importance of an accurate diagnosis of patients presenting with rhinitis symptoms and the morbidity of SAR obviously depends on the geographic region, the pollen season of the plants, and the local climate.

TL;DR: High‐mobility group box 1 protein (HMGB1), a nuclear protein that is released passively when necrotic cells lose the integrity of their membranes, acts in an autocrine/paracrine fashion and sustains long‐term repair and defense programs.